Skip to main content
OpenTrials
Completed

NCT Number: NCT05478460

Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer

The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Lung Cancer Lung Diseases Lung Neoplasms Neoplasms Neoplasms by Site Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

270 Dongan Road, Fudan University Shanghai Cancer Center

Shanghai, 200032, China

About this study

Postoperative pain after thoracic surgery has gained recognition as a adverse outcome and head-scratching problem. The incidence of choric postoperative pain (CPSP) in thoracic surgery has been reported to be 20%-80%. However, there has been not an standard treatment for CPSP. Many study has showed the risk factors of CPSP in thoracic surgery, such as VATS type, operation time, duration of drainage, preoperative pain, repeat surgery, gender, postoperative chemotherapy or radiation therapy , etc. It is important that moderate-to-severe acute postoperative pain will be transformed into CPSP. That offers a new management goal in postoperative pain prevention.CT-guided hookwire localization have been proven to be benefical for VATS to diagnose and treat small pulmonary , it can shorten operation timing and increase surgery success rate. However, it causes roughly 23.8% severe pain and complaints included wire dislodgement, pneumothorax and haemorrhage during and after insertion. The question is whether or not the moderate-to-severe acute postoperative pain from hookwire localition will change the incidence and intensity of CPSP in VATS.

Nurses play a pivotal role in advanced practice, research, and education in the field of pain management. The pain management of hookwire localization may be a new vison in further research.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 18-75
  • patients who underwent underwent CT-guided localization before VATS
  • ASA I-II
  • BMI 18.5-30
  • no serious complications after localization
  • sign informed consent

Exclusion criteria

  • could not complish underwent CT-guided localization
  • selfexpression or visual dysfunction
  • having emergency surgery
  • a severe psychiatric illness
  • having chronic pain problems in the chest area
  • Pregnant women

Treatment and study plan

Hookwire localization

Other

Patients were performed CT -guided hook wire localization(20G×120mm, PAJUNK medizintechnologie, Geisingen in Germany). patients were placed on a CT table in a suitable position(supine, prone, lateral) to obtain the shortest needle insertion route for their initial CT scan. Local anesthesia of the skin and planned puncture tract was performed using 10ml Lidocaine 1%. Next, the needle was inserted into or near the pulmonary nodule.

Primary outcomes

  1. postoperative incidence and intensity of chronic pain after surgery

    Time frame: at postoperative 3rd month

    the incidence and severity（11-point numerical rating scale,0=painless, 10=woest pain）of pain was assessed after VATS operation

  2. postoperative incidence and intensity of chronic pain after surgery

    Time frame: at postoperative 6th month

    the incidence and severity（11-point numerical rating scale, 0=painless, 10=worst pain）of pain was assessed after VATS operation

Secondary outcomes

  1. postoperative length of stay in hospital

    Time frame: an average of 1 week

    the days between postoperative 1st day and day of discharge from hospital

  2. satisfactory score

    Time frame: from the day discharge from hospital to postoperative 6th month

    Likert score (from 1 to 5),higher scores mean a better outcome

  3. intensity of postoperative acute pain

    Time frame: from immediately after surgery(at postanesthesia care unit ) to postoperative 2nd day

    the severity(11-point numerical rating scale, 0=no pain, 10=worst pain) after VATS operation

Sponsors and collaborators

Lead sponsor

Fudan University

Other

Registry information

Official study title

Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer in Patients With Preoperative CT-guided Hookwire Localization

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jul 28, 2022
Registry last updated
Oct 24, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.