Acupoint Thermal Radiation Characteristics in Adolescents with MDD

A total of 100 subjects were included, 60 adolescent with MDD (MDD group) and 40 healthy controls (HC group). All subjects accepted IRT detection.The random selection of 30 adolescent with MDD allowed the collection of the bilateral same name acupoint temperatures. Intra- and inter-observer reproducibility for the patients were examined in some randomly selected patients by 2 investigators and 2 investigators both made 2 independent measurements in a week. 30 MDD subjects were detected the bilateral same name acupoint temperatures.

Inclusion criteria

Inclusion criteria

for the healthy control participants:

• 12years≤ age<18 years;
• SDS score <53;
• Adolescents with normal cognitive function can cooperate with the study;
• Adolescents and guardians agree to the study plan and sign the informed consent form.

Inclusion criteria

for the major depression disorder participants:

• 12years≤ age<18 years;
• Self-rating Depression Scale (SDS) score ≥ 53;
• Language, cognition and communication ability are normal;
• Patients and guardians agree to the study plan and sign the informed consent form.

Exclusion criteria

Exclusion criteria

both for the healthy control participants and major depression disorder participants:

• Severe anxiety, schizophrenia, or other serious mental illnesses;
• There are pigmentation, redness, infection or scarring on the skin at the site of detection;
• Patients with severe systemic diseases and their complications, serious infections, and major diseases of viscera, tissues, and systems;
• Female patients who were pregnant or lactating;
• Female patients who were during, or in proximity (±2 days) to their menstruation or ovulation;
• Patients with a body temperature ≥37.3°C;
• Inability to cooperate during the examination;
• Participating in any other clinical trials.