Affiliated hospital of Chengdu University of TCM
Chengdu, Sichuan, 610072, China
NCT Number: NCT02029118
Hypothesis: acupoint application is effective for managing chronic stable angina pectoris. Aim: to evaluate the efficacy and safety of acupoint application on the specific acupoints for chronic stable angina pectoris. Design: A Randomized, Controlled,Double Blind trial. 200 participants will be included. Four arms: herbal medicine application on acupoint group , placebo application on acupoint group , herbal medicine application on non-acupoint group and placebo application on non-acupoint group.
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Notify Me35 year–85 year
All sexes
Interventional
Early Phase 1
Chengdu, Sichuan, 610072, China
Acupoint application with herbal medicine is a kind of external treatment of traditional Chinese medicine and has a long history in China, which is use herbal medicine made of plaster and stick to specific acupoints, using the double effects of acupoints and herb to treat disease. In China, acupoint application with herbal medicine has been used in clinical treatment of angina pectoris, but there is no convincing evidence for the efficacy of acupoint application for angina pectoris, due to low methodologic quality and small sample size. The investigators designed the Randomized, Controlled, Double Blind clinical trial to investigates the efficacy of acupoint application in treating angina pectoris, the purpose of this study is to provide the convincing evidence for acupoint application treatment of angina pectoris.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
1.Meet the diagnostic criteria of American College of Cardiology(ACC)/American Heart Association (AHA) angina pectoris of coronary heart disease.
2.35 ≤ age ≤ 85 years, both male and female.
3.The onset of angina pectoris≥3 months, and the frequency of angina attack≥2 a week.
4.Patients signed the informed consent
Exclusion criteria
Application containing herbal medicine that mainly include styrax, borneol, frankincense, santalum,trichosanthes kirilowii Maxim, allium macrostemon Bunge, leech and other herbal medicine.
Other names: Herbal medicine application
select acupoint according to traditional Chinese medicine
Other names: acupuncture point
foundation treatment
Other names: basic treatment
Time frame: at baseline,4, 8weeks after inclusion
The change frequency of angina attack during every 4-week.
Time frame: at baseline,4, 8weeks after inclusion
The VAS score evaluation angina pain severity
Time frame: at baseline,4, 8weeks after inclusion
Observed reduction in the dose of nitroglycerin
Time frame: at baseline,4, 8weeks after inclusion
Time frame: at baseline,4, 8weeks after inclusion
Time frame: at baseline,4, 8weeks after inclusion
Chengdu University of Traditional Chinese Medicine
Other
Effect of Acupoint Application With Herbal Medicine in Patients With Stable Angina Pectoris: Randomized, Controlled,Double Blind Clinical Study
Acronym: AASAP
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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