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OpenTrials
Completed

NCT Number: NCT00767975

Active Screening of Latent TB Infection, Treatment and Long Term Follow-up in Prison

LTBI Treatment is effective in prison

Completed

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Key information

Conditions

Tuberculosis Actinomycetales Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Positive Bacterial Infections Infections Mycobacterium Infections

Sex eligibility

Male

Study type

Interventional

Phase

Phase 3

Primary location

Taipei Prison

Taoyuan, Taiwan

About this study

LTBI treatment will be conducted in a prison with either isoniazid or rifampin

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all people who is LTBI, and have ability to sign the informed concent

Exclusion criteria

  • previously adverse effect from anti-TB medication complete treatment of TB in the pass; active TB AST, ALT > 3 times of normal limit platelet < 150 k/mm3 T-bil > 2 times of normal limit

Treatment and study plan

isoniazid , randomized, open label

Drug

isoniazid 300mg/tab 1 tab qd, 6 months (the other treatment arm is rifampin)

rifampin, randomized, open label

Drug

rifampin 300mg/capsule 2 caps qd, 4 months (the other treatment arm is isoniazid)

Primary outcomes

  1. COMPLETE RATE OF LTBI TREATMENT

    Time frame: 1.5 year

Secondary outcomes

  1. Efficacy

    Time frame: 3 year

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Acronym: LTBI_prison

Important dates

Study start
2008
Primary completion
2010
Study completion
2010
First posted
Oct 7, 2008
Registry last updated
Nov 29, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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