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NCT Number: NCT06552078

Activation of Biobank Registry for Bilio-pancreatic Diseases

The purpose of establishing the biobank is to create a collection of biological material and clinical data, with a prospective and retrospective mold, in order to investigate the role of genetic predisposition in multifactorial bilio-pancreatic diseases, so that an evaluation of the possible association in the pathogenesis of exogenous factors with endogenous factors can be allowed.

Multifactorial diseases are in fact an expression of genetic predisposition upon which one or more environmental stimuli act. Usually the aforementioned factors are not capable individually of triggering disease but, when simultaneously present, can cause the pathological phenotype. Therefore, it becomes important in the description of disease pathogenesis to identify as many risk factors for disease prevention and early diagnosis.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

IRCCS OSpedale San Raffaele

Milan, 20132, Italy

Location status: Recruiting

Location contact

Gabriele Capurso, MD

CONTACT

[email protected]

02/26436548

Laura Apadula, MSN

CONTACT

[email protected]

02/26433979

About this study

Samples collected depending on the disease:

  • Peripheral blood;
  • Portal blood;
  • Saliva;
  • Urine;
  • Stool;
  • Cystic fluid;
  • Pancreatic juice;
  • Biopsy tissue specimens;

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age >= 18 years
  • signed informed consent

Exclusion criteria

  • age < 18 years
  • unwilling to sign informed consent

Treatment and study plan

Primary outcomes

  1. The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers

    Time frame: Tthrough study completion, an average of 1 year

    The rate of patients with each pancreatic disorder presenting with certain exposures or certain biomarkers will be evaluated by descriptive statistics and when available compared with that of subjects without such disorders (controls).

Study contacts

Contact information is provided by the study sponsor or research team.

Gabriele Capurso, MD

CONTACT

[email protected]

02/26436548

Laura Apadula, MSN

CONTACT

[email protected]

02/26433979

Sponsors and collaborators

Lead sponsor

IRCCS San Raffaele

Other

Registry information

Official study title

Activation of Biobank for Association Study Between Environmental and Genetic Factors in Inflammatory, Functional and Neoplastic Bilio-pancreatic Diseases

Acronym: BIO-PANCREAS

Important dates

Study start
2021
Primary completion
2027
Study completion
2030
First posted
Aug 13, 2024
Registry last updated
May 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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