Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

To demonstrate that treatment of actinic keratoses and photodamage with a combination of Ameluz and Broad Band Light (BBL) will lead to an improvement in facial precancerous change and signs of photodamage.

Inclusion criteria

• Over 18yrs of age
• Willingness to participate in all required study activities and visits
• Willingness to sign the informed consent form
• Visible and palpable signs of diffuse actinic damage and actinic keratoses of mild to moderate severity located on the face
• Significant signs of photoaging, evaluated by investigator, that include any or all the following:

• Dyspigmentation
• Solar lentigines
• Telangiectasias
• Diffuse erythema
• Roughness and other textural changes
• Fine lines
• Wrinkles
• Actinic bronzing

Exclusion criteria

• Subject who is unable and unwilling to provide consent for study schedule and procedures
• Subject who is pregnant or trying to become pregnant during the study
• Subjects using any topical treatment on their AKs; must stop at least one month prior
• Subjects currently undergoing cancer treatment with medical or radiation therapy
• Subjects with a known hypersensitivity to 5-aminolevulinic acid or any component of the study material
• Subjects with history of a photosensitivity disease, such as porphyria cutanea tarda