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NCT Number: NCT06552013

Action Towards Health Equity and Improved Air Quality in the Duwamish Valley: A Multilevel Asthma Intervention

The goal of this randomized control trial is to learn if box fans and filters can reduce asthma symptoms and improve indoor air quality in children ages 6 - 17 years old with asthma living in the Duwamish Valley, Seattle, Washington. The main question it aims to answer are:

* Do box fans with filters improve asthma symptoms? * Do box fans with filters improve an objective measure used to monitor lung function known as forced expiratory volume during the first second (FEV1)? Researchers will compare children living in households with high quality filters to those in households with sham filters to see if air quality and asthma symptoms improve.

Participants will

* fill out several questionnaires * monitor their lung function with a peak flow meter * place an air monitor in their homes to monitor indoor air quality * run the box fan when they are at home

Recruiting

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Key information

Conditions

Asthma in Children

Age range

6 year–17 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Duwamish River Community Coaltion

Seattle, Washington, 98108, United States

Location status: Recruiting

Location contact

Joseph Santana, MPH

CONTACT

[email protected]

253-235-9148

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age (6-17 years)
  • poorly controlled physician diagnosed asthma defined as more than four days with asthma symptoms in the past two weeks, use of asthma rescue medication for more than four days in the past two weeks, or health care utilization due to asthma in the past year (hospitalization, emergency room visit, or unscheduled clinic visit)
  • living in Georgetown and South Park neighborhoods of Seattle

Exclusion criteria

  • children with unstable housing or shared custody arrangements

Treatment and study plan

MERV 13 filter

Other

This is an environmental intervention consisting of a low-cost box fan with a MERV 13 filter placed behind it. The company Lasko makes these fans and other environmental appliances.

Sham filter

Other

This is an environmental intervention consisting of a low-cost box fan with a sham filter (MERV 1) placed behind it. The company Lasko makes these fans and other environmental appliances.

Primary outcomes

  1. Asthma symptoms

    Time frame: ACQ will be measured weekly for 6 consecutive weeks, two pre-intervention weeks (before box fans have been given to participant) and four weeks while fans are being used in the home. Symptoms will also be assessed at the six month follow-up visit.

    Symptoms are evaluated with the seven-item asthma control questionnaire (ACQ), a validated tool used in children.

  2. FEV1

    Time frame: FEV1 measures will be taken daily, once in the morning and once at night for the six week study time frame. Prior to the six month follow up we will ask participants to take three consecutive days of FEV1 measurements, for an additional 6 measures

    FEV1 is captured with a digital peak flow meter.

Secondary outcomes

  1. Asthma quality of life

    Time frame: Will be evaluated at baseline (visit 1), after 6 weeks (visit 3) and at 6 month follow up (visit 4)

    Will be assessed with the15-item mini-asthma quality of life questionnaire, a validated tool

  2. Use of rescue medications

    Time frame: ACQ will be measured weekly for 6 consecutive weeks, two pre-intervention weeks (before box fans have been given to participant) and four weeks while fans are being used in the home. Symptoms will also be assessed at the six month follow-up visit.

    This is an item on the ACQ. See primary outcome.

  3. Health care utilization in the past month

    Time frame: Will be evaluated at baseline (visit 1), after 6 weeks (visit 3) and at 6 month follow up (visit 4)

    Will be assessed with the six-item asthma-related health care utilization questionnaire.

Study contacts

Contact information is provided by the study sponsor or research team.

Anjum Hajat, PhD, MPH

CONTACT

[email protected]

206-685-3618

Sponsors and collaborators

Lead sponsor

University of Washington

Other

Collaborators

  • National Institute of Environmental Health Sciences (NIEHS)

Registry information

Acronym: DAISY

Important dates

Study start
2024
Primary completion
2028
Study completion
2028
First posted
Aug 13, 2024
Registry last updated
Aug 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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