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Completed

NCT Number: NCT06166875

Accuracy of IVCCI as a Measure of CVP

The primary aim of the current study is to examine the accuracy of IVCCI for measurement of CVP and to derive equation or formula to predict CVP from IVCCI.

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Key information

Conditions

IVC Collapsibility Index

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Anesthesiology, Intensive Care, and Pain Management, Faculty of Medicine, Ain Shams University

Cairo, 11517, Egypt

About this study

Hemodynamic monitoring is important in the management of patients in the intensive care unit (ICU) Assessment of the intravascular volume, infusion of fluids or vasoactive drugs and maintenance of an adequate systemic perfusion is essential for reduction of the risk of organ failure and/or mortality.

The use of CVP through central venous catheter is a gold standard method that is extensively used in the ICU as it reflects the filling pressure of the right ventricle (RV) and RV preload.

Central venous cannulation has significant complications such as pneumothorax, hemothorax, arterial puncture, catheter malposition, cardiac arrhythmias, venous embolism, subcutaneous hematoma, and catheter related infection, and it is difficult to use this method in an emergency situation as it requires skilled personnel.

Measurement of IVC index by bedside ultrasound is widely used to assess the intravascular volume in adult patients and has the advantage of being non-invasive, rapid, and reliable for assessing the volume status.

Besides, related measures such as IVC diameter, IVC collapsibility, and IVC to aorta (AO) diameter have been applied clinically to assess the volume status and have been related to CVP.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age: ≥18 years.
  • Sex: Both sexes.
  • BMI: <35
  • Patient in whom central venous cannulation is needed for management.
  • Spontaneously breathing patients.

Exclusion criteria

  • Patients with increased intra abdominal pressure.
  • Patients who not able to lie supine.
  • Patients on mechanical ventilation.

Treatment and study plan

Primary outcomes

  1. The primary outcome of the current study is to examine the accuracy of IVCCI for measurement of CVP and to derive equation or formula to predict CVP from IVCCI.

    Time frame: 18 months

Sponsors and collaborators

Lead sponsor

Nermeen Shawky Ahmed Mohamed

Other

Registry information

Official study title

Accuracy of Inferior Vena Cava Collapsibility Index as a Measure of Central Venous Pressure

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Dec 12, 2023
Registry last updated
May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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