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OpenTrials
Completed

NCT Number: NCT06750822

Accuracy of Automatic Contusion Volume Scanning for Predicting the Incidence of Pneumonia in Patients With Thoracic Trauma

The goal of this retrospective observational study is to evaluate the diagnostic accuracy of pulmonary contusion volume in predicting early pneumonia in patients with thoracic trauma.

The primary question we aim to answer is: What is the diagnostic accuracy of pulmonary contusion volume in predicting pneumonia within 7 days post-trauma?

Moreover, we aim to explore which is the overlap between the contused segments and those developing pneumonia.

Finally, we aim to explore relevant differences in radiomic features between contused segments that developed pneumonia.

Completed

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Key information

Conditions

Pneumonia Infections Lung Diseases Respiratory Tract Diseases Respiratory Tract Infections Thoracic Trauma Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Maggiore Hospital Carlo Alberto Pizzardi

Bologna, BO, 40128, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Admission to the ED for trauma as primary diagnosis
  • Whole-body contrast CT scan performed within 6 hours from admission

Exclusion criteria

  • Age <18 years

Treatment and study plan

Primary outcomes

  1. 7d-pneumonia

    Time frame: 7 days

    Pneumonia appearing within 7 days from trauma, defined as:

    • New or worsening pulmonary infiltrates plus ≥ 2 of the following:
    • Body temperature ≥ 38°C or ≤ 35°C
    • White Blood Cell (WBC) count > 12,000 or < 4,000 cells/mL or presence of immature granulocytes in the blood sample
    • Purulent sputum
    • Worsening pulmonary oxygenation, defined as a decline in the PaO2/FiO2 ratio

Sponsors and collaborators

Lead sponsor

Azienda Usl di Bologna

Other Gov

Registry information

Acronym: RESOLUTION

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Dec 27, 2024
Registry last updated
Dec 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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