Acclimatization Mechanisms During Ascent to 7500m

The trial evaluates the role of ascent protocol on acute mountain sickness and cardio-respiratory physiology during an ascent to Muztagh Ata (7546m). Two groups of mountaineers ascend with different acclimatization time to the summit. The prevalence and severity of symptoms of acute mountain sickness are evaluated along with physiologic variables.

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Key information

Conditions

Acute Mountain Sickness Altitude Sickness Hypoxia Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Tract Diseases Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy, physically fit subject
Mountaineering experience

Exclusion criteria

Any type of cardiac or respiratory disease
Regular intake of any medication
History of high altitude pulmonary oedema
Severe acute mountain sickness at altitudes below 3500m or high altitude cerebral oedema.

Treatment and study plan

ascent protocol

Behavioral

ascent protocol for the two groups has different acclimatization time

Primary outcomes

acute mountain sickness

Time frame: during ascent

Secondary outcomes

mountaineering success, oxygen saturation, breathing pattern

Time frame: during ascent

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Collaborators

Swiss National Science Foundation

Registry information

Official study title

Acclimatization Mechanisms During Ascent to 7500m. Effects of Ascent Protocol on Acute Mountain Sickness and Cardiorespiratory Physiology

Important dates

Study start: 2005
Primary completion: 2005
Study completion: 2005
First posted: Jan 28, 2008
Registry last updated: May 20, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed