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NCT Number: NCT07492797

Accessible Remote Rehabilitation System for Real-Time Biomechanical Monitoring

This study evaluates a novel camera-based system designed to support remote rehabilitation by measuring hand and upper-limb biomechanics in real time. Many patients recovering from musculoskeletal or neurological conditions require frequent monitoring during rehabilitation, but regular clinic visits may be difficult due to distance, cost, or limited access to specialized care. Current telehealth approaches typically rely on qualitative assessments or self-reported feedback rather than objective biomechanical measurements.

The purpose of this study is to determine whether a computer vision-based system can accurately estimate biomechanical parameters such as joint angles, range of motion, muscle force, and joint torque using only a standard camera. The system analyzes hand movement using artificial intelligence and biomechanical modeling to provide real-time measurements during rehabilitation exercises.

Participants will perform guided hand-movement tasks while the system records video and extracts anatomical landmarks. These data will be used to compute biomechanical parameters and assess whether the system can reliably monitor rehabilitation progress remotely. The results will help determine whether this technology can provide clinicians with objective, continuous data to support personalized rehabilitation and improve patient outcomes.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Mississippi Medical Center, Jackson, Mississippi, United States

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About this study

This study aims to develop and validate a camera-based tele-rehabilitation platform capable of estimating biomechanical parameters of the human hand and upper limb in real time. Musculoskeletal and neurological conditions often require continuous monitoring during rehabilitation, yet many patients-particularly those in rural or underserved regions-have limited access to frequent in-person therapy sessions. Existing telehealth systems primarily rely on subjective reporting or periodic video consultations and often lack quantitative biomechanical measurements necessary for precise monitoring of recovery.

The objective of this research is to evaluate whether computer vision and biomechanical modeling can provide accurate, quantitative measurements of joint motion and force using a single camera. The central hypothesis is that artificial intelligence algorithms can detect anatomical landmarks of the hand from video data and combine them with mechanical modeling techniques to estimate joint angles, torques, and muscle forces in real time. Continuous biomechanical tracking may allow clinicians to better monitor rehabilitation progress and make timely adjustments to therapy protocols.

Participants will perform standardized hand-movement exercises while video data are captured using a consumer-grade camera such as a smartphone or laptop camera. Computer vision algorithms will identify hand landmarks and calculate joint kinematics. These measurements will then be integrated with inverse dynamics modeling to estimate biomechanical parameters including joint torque, range of motion, and force generation.

The study will evaluate the reliability and validity of the proposed system by comparing the computed biomechanical measurements with established biomechanical models and reference datasets. Key outcomes include the accuracy of landmark detection, reliability of biomechanical parameter estimation, and feasibility of remote monitoring during rehabilitation exercises.

Successful completion of this study will demonstrate the feasibility of a low-cost, accessible tele-rehabilitation platform capable of delivering objective biomechanical feedback to clinicians and patients. This approach has the potential to improve access to rehabilitation services, enhance patient engagement, and support data-driven clinical decision-making in remote healthcare settings.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18 years or older.
  • Individuals undergoing or recovering from upper-limb or hand rehabilitation following musculoskeletal or neurological injury or surgery.
  • Ability to perform basic hand or upper-limb movement tasks required for the rehabilitation exercises.
  • Ability to understand study instructions and provide informed consent.

Exclusion criteria

  • Severe cognitive impairment preventing understanding of study procedures.
  • Medical conditions that prevent safe participation in hand or upper-limb rehabilitation exercises.
  • Severe visual impairment preventing interaction with the camera-based monitoring system.
  • Participation in another interventional study that could affect rehabilitation outcomes.

Treatment and study plan

AI-Based Camera Tele-Rehabilitation Monitoring System

Device

A single-camera, computer vision and inverse-dynamics modeling system that estimates biomechanical parameters (joint torque, muscle force, and range of motion) from video-based hand landmark tracking during rehabilitation exercises.

Standard Telehealth Rehabilitation

Behavioral

Participants perform standard rehabilitation exercises and receive routine telehealth follow-up with clinicians according to usual care practices. No camera-based biomechanical monitoring system is used during the rehabilitation process.

Primary outcomes

  1. Accuracy of Camera-Based Joint Torque Estimation

    Time frame: Baseline assessment session

    Accuracy of the AI-based camera system in estimating joint torque during rehabilitation exercises compared with gold-standard dynamometer measurements. Accuracy will be evaluated using mean absolute percentage error (MAPE) between estimated torque values and reference dynamometer readings.

  2. Correlation Between Camera-Based and Clinical Biomechanical Measurements

    Time frame: Baseline assessment session

    Agreement between biomechanical parameters estimated by the camera-based system and reference clinical measurements. Pearson correlation coefficients and Bland-Altman analysis will be used to evaluate agreement between estimated joint torque and gold-standard measurements.

Secondary outcomes

  1. Grip Strength Improvement

    Time frame: Baseline, 3 weeks, and 6 weeks

    Change in hand grip strength measured using a clinical dynamometer during the rehabilitation program.

  2. Range of Motion Improvement

    Time frame: Baseline, 3 weeks, and 6 weeks

    Change in hand and finger joint range of motion measured using standard clinical goniometry during the rehabilitation period.

  3. Functional Recovery Time

    Time frame: Up to 6 weeks

    Time required for participants to regain at least 80% of their pre-injury hand function based on clinical functional assessments.

  4. Patient Adherence to Rehabilitation Exercises

    Time frame: Up to 6 weeks

    Participant adherence to prescribed rehabilitation exercises measured by completion rate of assigned therapy sessions during the study period.

Study contacts

Contact information is provided by the study sponsor or research team.

Soroush Korivand, PhD

CONTACT

[email protected]

662-325-9154

Sponsors and collaborators

Lead sponsor

Mississippi State University

Other

Collaborators

  • University of Mississippi Medical Center

Registry information

Official study title

Development and Clinical Validation of an AI-Based Camera System for Real-Time Biomechanical Monitoring in Upper-Limb Rehabilitation

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Mar 25, 2026
Registry last updated
May 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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