Skip to main content
OpenTrials
Completed

NCT Number: NCT04338789

Accelerated Mandibular Molar Protraction: Piezocision at the Time of Molar Protraction or Later?

This study was conducted to compare the rate of second molar protraction, level of Interleukin1-β in gingival crevicular fluid, periodontal health (gingival index, plaque index, and periodontal pocket depth) and root resorption in patients treated by molar protraction with piezocision performed early at the time of protraction (Group 1), piezocision performed 3 months after molar protraction (Group 2), and no piezocision molar protraction (Group 3).

Completed

Looking for future studies?

Notify Me

Key information

Age range

19 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Detailed Description: Thirty-five subjects who presented with bilaterally extracted mandibular first molar were selected to participate in the study. The subjects were subdivided into one of 3 groups as follows: group 1 consisted of 20 subjects /20 molars where piezocision was performed immediately before molar protraction; group 2 consisted of 20 subjects/ 20 molars where molar protraction was carried on after 3 months of molar protraction with no piezocision; group 3 consisted of 20 subjects (40 molars) where protraction was carried out with no piezocision.

After reaching 0.019X0.025" SS arch wire, NiTi coil spring was used for space closure (protraction force was 150g) attached from the lower second molar hook to the head of the mini-screw. Piezocision was performed by making 2 vertical incisions mesial and distal to the extraction space. Piezotome was inserted in the incisions previously made and bone cuts were done with a length up to mucogingival line and depth of 3 mm. Gingival crevicular fluid (GCF) sample was obtained from the mesiogingival side of the lower second permanent molar with use of Periopaper. GCF sample was repeated 1 day, 1 week and 4 weeks after molar protraction with piezocision or with no piezocision. Periodontal parameters were measured and lower molar root resorption was assessed using Perapical radiographs.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age range from 19 to 30 years
  • Bilaterally extracted mandibular first molar (first molar extracted more than one year ago and with a residual extraction space of more than 6 mm).
  • Class 1 malocclusion where molar protraction is indicated.
  • All permanent teeth are present except for the extracted mandibular first molars.
  • Healthy periodontium (gingival index score ≤ 2, plaque index score ≤ 2 and probing depth < 4mm)

Exclusion criteria

  • Previous orthodontic treatment
  • Any systemic disease
  • Smoker
  • Poor Oral hygiene

Treatment and study plan

Piezocision

Other

Piezocesion was performed by making 2 vertical incisions mesial and distal to the extraction space. Piezotome was inserted in the incisions previously made and bone cuts were done with a length up to mucogingival line and depth of 3 mm.

Primary outcomes

  1. Rate of molar protraction

    Time frame: 1 year

    Measured in mm/month from dental casts

  2. Changes in the level of of Interleukin1-β

    Time frame: 4 weeks

    Detected in Gingival crevicular fluid (GCF). The periopaper was placed for 60 seconds in the mesiogingival sulcus of the lower second permanent molar and was transferred to an Eppendorf tube containing phosphate buffered saline.

Secondary outcomes

  1. Periodontal parameters (Plaque, gingival health, periodontal pocket depth, alveolar bone height)

    Time frame: 1 year

    Plaque and gingival health are measured using plaque index and gingival index. pocket depth and alveolar height are measured in mm.

  2. Lower molar root resorption

    Time frame: 1 year

    Length of lower second molar roots in mm

Sponsors and collaborators

Lead sponsor

Jordan University of Science and Technology

Other

Registry information

Official study title

Mandibular Molar Protraction Assisted by Temporary Anchorage Device and Piezoelectric Corticotomy

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Apr 8, 2020
Registry last updated
Apr 8, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.