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Completed

NCT Number: NCT00721643

Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.

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Key information

Conditions

Oxidative Stress

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University

Boston, Massachusetts, 02111, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects (>60 yr, n=5)
  • subjects with metabolic syndrome (>60 yr, n=5)
  • Subjects who has
  • high fasting plasma glucose (>5.6 mmol/L),
  • central obesity (waist-hip ratio, >0.9 for men, >0.85 for women)
  • either high blood pressure (>130/85 mmHg) or high triacylglycerol (>1.7 mmol/L) will be selected to have metabolic syndrome.
  • normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function
  • no history of smoking or alcoholism.

Exclusion criteria

  • consume >7 alcoholic drinks/wk
  • taking cholesterol medication or hormone replacement

Treatment and study plan

angel's plant (Angelica keiskei)

Dietary Supplement

Healthy control, one time dose of 5g dry power of Angelica keiskei

Primary outcomes

  1. Plasma quercetin

    Time frame: 0, 30, 60, 100, 180, 240, 300, 360, 420 & 480 min

Sponsors and collaborators

Lead sponsor

Tufts University

Other

Registry information

Important dates

Study start
2008
Primary completion
2009
Study completion
2010
First posted
Jul 24, 2008
Registry last updated
Apr 25, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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