Abdominal Wall Closure With Triclosan-coated Suture

After open colorectal surgery the surgical site infection (SSI) is very high among abdominal surgeries. The goal of our randomized, prospective, multicentric, internet-based study is to compare rate of SSI after surgery of colon and rectum by using triclosan-coated suture for abdominal wall closure. Two arms are separated by computer randomization at abdominal wall closure: application of triclosan-coated and non-coated PDS suture (PDS versus PDS-Plus). Triclosan is an antiseptic material which we hope provides better local infection control at the site with reducing the risk of bacterial colonisation.

attached website: www.itplan.hu/sebstudy/ Randomizing patients: 1. logging in (completing the ID panel) 2. on-line randomization 3. patient appears on list 4. operation (recording details) 5. recording - post-operation events

• complications
• control examination

Inclusion criteria

• Elective (subjected to bowel preparation) operations
• Benign or malignant colon or rectal disease
• Age: 18-80
• Bowel opening is made during operation

Exclusion criteria

• Cannot be randomized:

• Systemic diseases influencing local surgical site healing
• Insulin-dependent diabetes mellitus
• Child B-C liver cirrhosis
• Kidney disease requiring dialysis
• Immune-suppression treatment
• IBD
• Acute surgery or unprepared bowel
• After being informed patient does not sign the statement of consent
• To be excluded later:

• Surgically incurable tumour
• Septic state or complication occurred in the post-operational stage
• Patient withdraws the signed consent before the examination is closed
• Undesirable complication:

• Sterile surgical site separation
• Suture break during the post-operational stage