University of Kentucky
Lexington, Kentucky, 40536, United States
Location status: Recruiting
Location contact
Anna Hoover, PhD
CONTACT
Jason Unrine, PhD
CONTACT
Recruiting
NCT Number: NCT05172752
A University-Community Partnership to Reduce Exposure to Disinfection Byproducts In Appalachia
Appalachian Kentuckians in Martin and Letcher Counties are grappling with a health-threatening drinking water crisis arising from exposures to disinfection by-products (DBPs). DBPs include trihalomethanes (THMs), haloacetic acids (HAAs), chlorate, and other compounds that have been associated with a variety of adverse health effects, including increased risk of bladder cancer and cardiovascular birth defects. This study implements a multi-stakeholder, multi-method approach to improve understanding of, characterize spatial and temporal variations in, and reduce exposure to DBPs in these Appalachian Kentucky counties.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Located in Martin or Letcher County water districts
- At least 18 years old
- Able to read/speak in English
Exclusion criteria
- Located outside of Martin or Letcher County water districts
Treatment and study plan
Citizen Scientist Training Program
OtherCitizen Scientist Training Program Participants is a three year training and in-home sampling program for disinfection byproducts. Participants will be trained and assessed based on their experience in the training program.
Stakeholder Consultation Core Program
OtherStakeholder Consultation Core Program Participants is a five year assessments where participants will participate in quarterly meetings and deliberative activities related to disinfection byproducts. Participants will be assessed based on their experience in the program.
Primary outcomes
-
Change in Environmental Health Literacy (EHL) - Knowledge
Time frame: Baseline, 5-years
Study participants will complete pre-/post-surveys of disinfection byproducts-related knowledge. Participants will answer 21 questions with multiple choice or fill in the blank response options that will be assessed for correctness/completeness.
-
Change in Environmental Health Literacy (EHL) - Attitudes/Behaviors
Time frame: Baseline, 5-years
Study participants will complete pre-/post-surveys of disinfection byproducts-related attitudes. Participants will answer 9 questions related attitudes/behaviors with a five-point Likert scale, ranging from Strongly Disagree to Strongly Agree, where Strongly Agree indicates a greater likelihood for the behavior/more positive attitude.
-
Change in participant network density
Time frame: Baseline, 5-years
The proportion of direct ties within the network as compared to the number of possible ties as measured by an unbounded social media analysis.
-
Change in participant centrality
Time frame: Baseline, 5-years
The influence of each individual within the network (i.e., betweenness and degree centrality) as measured by an unbounded social media analysis.
-
Change in participant reciprocity
Time frame: Baseline, 5-years
The number of reciprocal ties, which is the extent to which individuals within the network recognize each other as valued resources/collaborators as measured by an unbounded social media analysis.
Study contacts
Contact information is provided by the study sponsor or research team.
Anna Hoover, PhD
CONTACT
Jason Unrine, PhD
CONTACT
Sponsors and collaborators
Lead sponsor
Anna Hoover
Other
Collaborators
- National Institute of Environmental Health Sciences (NIEHS)
Registry information
Important dates
- Study start
- 2022
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Dec 29, 2021
- Registry last updated
- May 4, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.