Griffith University, Gold Coast Campus
Southport, Queensland, 4222, Australia
Location status: Recruiting
NCT Number: NCT07434752
The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.
Interested in participating?
Request Info18 year–45 year
All sexes
Interventional
Phase 4
Southport, Queensland, 4222, Australia
Location status: Recruiting
This study investigates whether consuming an energy drink containing caffeine and green tea extract before exercise increases fat burning (oxidation) compared with a placebo drink. Healthy, moderately active adults will attend three visits at clinic over 3-5 weeks. The first visit determines each participant's individual exercise intensity that maximises fat use during cycling. At two subsequent visits, participants will consume either the active drink or a placebo before completing a 30-minute cycling session at their personalised intensity. Fat and carbohydrate use, heart rate, blood pressure, and subjective responses will be measured at rest, during exercise, and after exercise using a double-blind, crossover design.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Two 355 mL cans of "XS Energy + BURN" drink containing caffeine and green tea extract.
Other names: XS Energy + BURN
Two 355 mL cans of placebo drink but without the active ingredients (caffeine and green tea extract).
Time frame: Baseline to 30 mins post exercise
Change from baseline to the end of the study period in Fat oxidation as measured by indirect calorimetry (metabolic cart); baseline (pre-drink), post-drink (pre-exercise), time sequence e.g., every 5-min during exercise, 10, 20 and 30-min post-exercise. Change from baseline & total. Fat oxidation will be measured continuously throughout the exercise and the 30-min post-exercise window, to facilitate total, and any other temporal fat oxidation timepoints.
Time frame: Baseline to 30 mins post exercise
Change from baseline to the end of the study period in Carbohydrate oxidation; indirect calorimetry; same timing as fat oxidation (baseline (pre-drink), post-drink (pre-exercise), time sequence e.g., every 5-min during exercise, 10, 20 and 30-min post-exercise.). Change from baseline & total.
Time frame: Baseline to 30 mins post exercise
Change from baseline to the end of the study period in Respiratory exchange ratio; indirect calorimetry; same timing as fat oxidation (baseline (pre-drink), post-drink (pre-exercise), time sequence e.g., every 5-min during exercise, 10, 20 and 30-min post-exercise). Change from baseline & total
Time frame: Baseline to 30 mins post exercise
Change from baseline to the end of the study period in Exercise efficiency; indirect calorimetry; time sequence during exercise e.g., every 5-min. Change from the beginning of exercise & average
Time frame: Baseline to end of study period (week 5)
Compliance monitoring for adherence to clinical trial components e.g. consumed volume of investigational product; ability to complete the necessary duration (30 mins) and intensity (at fat max) of exercise; adherence to immediate pre-trial control procedures of no caffeine or green tea extract in the 12 hours leading up to the experimental, arrival at the laboratory after an overnight fast
Time frame: Baseline to end of study period (week 5)
Adverse events will be monitored throughout the study across the study periods.
Time frame: Baseline to end of study (week 5)
Change from baseline to the end of the study period in Perceived gastrointestinal (dis)comfort; measured via a questionnaire.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in Perceived satiety / hunger; measured via questionnaire.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in Perceived exercising exertion; measured via questionnaire.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in heart rate. Pre, during and post exercise heart rate.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in blood pressure. Pre, during and post exercise blood pressure.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in safety via AE monitoring.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in BMI.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in weight.
Time frame: Baseline to end of study period (week 5)
Change from baseline to the end of the study period in waist circumference.
Contact information is provided by the study sponsor or research team.
RDC Clinical Pty Ltd
Industry
Influence of Caffeine and Green Tea Extracts Consumption on Basal, Peri- and Post-exercise Fat Oxidation
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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