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Recruiting

NCT Number: NCT06291207

A Study to Evaluate the Efficacy and Safety of AD-224

The purpose of this study is to evaluate the efficacy and safety of AD-224

Recruiting

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Key information

Conditions

Hypertension,Essential Cardiovascular Diseases Essential Hypertension Hypertension Vascular Diseases

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Seoul National University Bundang Hospital

Seongnam-si, South Korea

Location status: Recruiting

Location contact

InHo Chae

CONTACT

About this study

Condition or disease : Essential Hypertension

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Signed informed consent
  • Patients with Essential Hypertension
  • Other inclusions applied

Exclusion criteria

  • Patient with Secondary Hypertension
  • Other exclusions applied

Treatment and study plan

AD-224A

Drug

PO, Once daily, 8weeks

AD-224B

Drug

PO, Once daily, 8weeks

AD-224C

Drug

PO, Once daily, 8weeks

Placebo of AD-224A

Drug

PO, Once daily, 8weeks

Placebo of AD-224B

Drug

PO, Once daily, 8weeks

Placebo of AD-224C

Drug

PO, Once daily, 8weeks

Primary outcomes

  1. Change rate of MSSBP

    Time frame: Baseline, Week 8

    Change from baseline in mean sitting systolic blood pressure

Study contacts

Contact information is provided by the study sponsor or research team.

JeongEun Park

CONTACT

[email protected]

+82-31-891-6989

Sponsors and collaborators

Lead sponsor

Addpharma Inc.

Industry

Registry information

Official study title

A Randomization, Double-blind, Active-controlled, Multicenter, Phase 3 Trial to Evaluate the Efficacy and Safety of AD-224A and AD-224B in Patients with Essential Hypertension

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Mar 4, 2024
Registry last updated
Feb 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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