Skip to main content
OpenTrials
Completed

NCT Number: NCT07740746

A Study to Evaluate the Effects of a Supplement on Mucus Clearance and Respiratory Symptoms

This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the BetterLungs Mullein + Chlorophyll supplement on mucus clearance and respiratory symptoms over 60 days. One hundred adult participants experiencing chest mucus build-up, difficulty clearing mucus, breathlessness, and low energy levels will be enrolled and randomized to either the active supplement or a matched placebo.

Participants will take their assigned product once daily in the morning mixed with water and will complete self-reported questionnaires at Baseline, Day 20, Day 40, and Day 60.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Mucus Clearance Breathlessness Chest Mucus Accumulation Dyspnea Low Energy Levels Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Symptoms Respiratory Tract Diseases Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Citruslabs

Las Vegas, Nevada, 89118, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be male or female
  • Be aged 18+
  • Anyone experiencing issues regarding all of the following over the past three months: a build-up of chest mucus, difficulty clearing chest mucus, breathlessness, and low energy levels
  • Anyone who is generally healthy - does not live with any uncontrolled chronic disease
  • Willing to refrain from taking any products, prescription medications, or supplements that target lung health, mucus, and energy levels during the test period
  • Willing to maintain your current diet, sleep schedule, and activity level for the duration of the study
  • Resides in the United States
  • Not currently partaking in another research study and will not be partaking in any other research study for the next 60 days and at any point during this study's duration
  • If currently taking prescription medication are willing to discuss it with their physician before participating in this study

Exclusion criteria

  • Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including kidney disease, diabetes, cancer, mental health disorders, history of serious illness in the last three months, history of substance abuse, or planned surgery during the study period
  • Anyone who drinks heavily (i.e. 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men)
  • Anyone with a copper sensitivity disorder (such as Wilson's disease or copper metabolism disorders)
  • Anyone with kidney disease
  • Anyone with diabetes
  • Anyone with any known allergies or hypersensitivities to any supplement product ingredients
  • Anyone who is currently pregnant, trying to conceive, or breastfeeding

Treatment and study plan

BetterLungs

Dietary Supplement

50 participants receive the BetterLungs Mullein + Chlorophyll supplement (ingredients: mullein leaf, chlorophyll, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days

Placebo

Dietary Supplement

50 participants receive a matched placebo product (ingredients: moss coloring jungle green color, violet color, spirulina, vegetable glycerin, purified water) taken once daily in the morning with the first meal of the day; 2 mL (two full droppers) mixed with 8 ounces of water for 60 days; the taste and appearance of the placebo are matched to the active product

Primary outcomes

  1. Change in mucus clearance

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Self-reported change in mucus clearance assessed via questionnaire

  2. Change in respiratory symptoms

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Self-reported change in respiratory symptoms assessed via questionnaire

Secondary outcomes

  1. Change in perceived mucus clearance

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Participant-perceived change in mucus clearance assessed via self-reported questionnaire

  2. Change in energy levels

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Participant-perceived change in energy levels assessed via self-reported questionnaire

  3. Change in shortness of breath

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Participant-perceived change in shortness of breath associated with physical activity assessed via self-reported questionnaire

  4. Change in breathing-related anxiety

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Participant-perceived change in breathing-related anxiety assessed via self-reported questionnaire

  5. Change in ease of breathing

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Participant-perceived change in ease of breathing assessed via self-reported questionnaire

  6. Change in general well-being

    Time frame: Baseline, Day 20, Day 40, and Day 60

    Participant-perceived change in general well-being assessed via self-reported questionnaire

Sponsors and collaborators

Lead sponsor

The Better Brand Inc.

Industry

Collaborators

  • Citruslabs

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Aug 3, 2026
Registry last updated
Aug 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.