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Completed

NCT Number: NCT07608016

A Study to Evaluate a Supplement Combination in Supporting Weight Loss, Metabolic Health, and Quality of Life

This consumer-use study evaluates the effects of a combined postbiotic and prebiotic supplement regimen on appetite control, cravings, metabolic health, energy, and quality of life in adults aged 18-65 years with a body mass index (BMI) between 25 and 30.

Participants will consume one capsule of resM™ GLP-1 Postbiotic and one scoop of resG prebeet ENERGY Prebiotic daily for 60 days. Data will be collected through daily check-ins, weekly surveys, and quality-of-life questionnaires administered through the Chloe mobile application.

The primary objective is to evaluate changes in appetite control and food cravings over 60 days of supplementation.

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Key information

Conditions

Weight Loss Body Weight Body Weight Changes Metabolic Health Pathological Conditions, Signs and Symptoms Quality of Life Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Able Biolabs, LLC

Birmingham, Alabama, 35203, United States

About this study

The GLP-1 Optimizer Bundle combines resM™ GLP-1 Postbiotic and resG prebeet ENERGY Prebiotic to support appetite control, cravings, metabolic health, energy, and lifestyle behaviors.

This is a prospective, open-label, single-arm consumer-use study conducted over 60 days in approximately 20 adults aged 18-65 years with BMI between 25 and 30.

Participants will consume:

one capsule of resM™ GLP-1 Postbiotic daily one scoop of resG prebeet ENERGY Prebiotic daily

Assessments will be collected electronically through the Chloe mobile application and include:

appetite and cravings surveys energy and mood assessments quality-of-life questionnaires lifestyle habit surveys consumer satisfaction assessments

The study aims to evaluate consumer-reported changes associated with daily supplementation and lifestyle guidance.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults aged 18-65 years BMI between 25 and 30 Generally healthy Willing to comply with study procedures Access to smartphone or internet-enabled device for electronic questionnaires

Exclusion criteria

Pregnant, planning pregnancy, or lactating History of bariatric surgery Prescription weight loss medication use within the past 90 days Current GLP-1 drug use History of substance abuse within the past 6 months Current use of supplements containing overlapping active ingredients Significant medical condition that may interfere with study participation or interpretation of results

Treatment and study plan

Combination Prebiotic and Postbiotic

Dietary Supplement

Participants will take a combined dosage of prebiotic and postbiotic.

Primary outcomes

  1. Change in Appetite Control and Food Cravings Survey Scores Over 60 Days

    Time frame: Baseline through Day 60

    Participant-reported appetite control and food cravings will be assessed using daily and weekly questionnaires administered through the Chloe mobile application. Survey responses will evaluate changes in hunger, cravings, satiety, and eating behaviors over the study period.

Secondary outcomes

  1. Change in Energy and Mood Survey Scores Over 60 Days

    Time frame: Baseline through Day 60

    Participant-reported energy levels and mood will be assessed using weekly questionnaires administered through the participant management application.

  2. Change in Quality-of-Life Questionnaire Responses Over 60 Days

    Time frame: Baseline, Day 30, and Day 60

    Quality-of-life assessments will evaluate participant-reported physical well-being, lifestyle habits, and overall satisfaction during the study period.

  3. Participant Satisfaction and Willingness to Continue Product Use at Day 60

    Time frame: Day 60

    End-of-study surveys will assess participant satisfaction, perceived benefits, and willingness to continue using the supplement combination.

Sponsors and collaborators

Lead sponsor

Able Biolabs, LLC

Other

Registry information

Official study title

A Consumer Study to Evaluate the Efficacy of a Postbiotic and Prebiotic Supplement Combination in Supporting Weight Loss, Metabolic Health, and Quality of Life

Acronym: RESMRESG101

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 27, 2026
Registry last updated
Jun 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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