A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders

Inclusion criteria

• Informed consent / Assent, as applicable must be signed prior to executing any study related procedure
• Children, male or female, 2 to 17 years old (inclusive)
• Confirmed diagnosis of ASD according to the diagnostic measures:

• DSM-IV Symptom Checklist
• Autism Diagnostic Observation Schedule(ADOS)&/or Autism Diagnostic Interview Revised(ADI-R)within 18 months prior to entry into the study
• Subjects must present with a current history of at least two of the following persistent GI symptoms as confirmed by the study physician:

• Diarrhea, as characterised by three or more loose stools a day for at least 8 out of 14 days
• Constipation as characterised by less than 3 bowel movements per week, for at least a 2-week period
• Esophageal reflux, as characterised by 3 or more episodes of regurgitation per day on 10 out of 14 days
• Abdominal pain manifested as pain after eating or self injurious behavior on at least 8 out of 14 days
• Suspected food allergy which is confirmed by a physician, as characterized as a recurrent reaction or association with specific foods
• Subject able to consume 3 tablespoons of study powder mixed in food daily for 12 weeks

Exclusion criteria

• Children with a history of anaphylaxis to dietary milk and wheat proteins
• Children with severe concurrent illness
• Children who are prescribed systemic steroids
• Children currently receiving chelation therapy, hyperbaric or antifungal treatment within 1 month of entry into the study and during the study period.
• Children with a confirmed diagnosis of celiac disease
• Subjects who have previously tried dietary elimination of casein and gluten for at least 1 month period and failed to demonstrate a response by parent perception
• Children who are unable to consume 3 tablespoons of study powder mixed in food daily for 12 weeks daily