A Study to Assess the Disturbances in Calcitonin Gene in Patients With Gum Disease and Osteoporosis

Periodontitis is a polymicrobial inflammatory disease which includes various modifiable and nonmodifiable risk factors. The non modifiable risk factors include genetic polymorphisms like metabolism associated genetic polymorphisms ( Vitamin D and Calcitonin).

Osteoporosis is a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue with consequent increase in bone fragility and susceptibility to fractures.

Bone loss is a common feature shared between periodontal disease and osteoporosis.

Out of all genetic factors Calcitonin gene polymorphism contributes to the development of both osteoporosis and chronic periodontitis.

Inclusion criteria

• Male and Female
• Patients aged between 35.00 Year(s) to 60.00 Year(s) diagnosed with Osteoporosis and Chronic Periodontitis who are willing to participate in the study

Exclusion criteria

• Patients who are Systemically compromised and under medications such as steroids.
• Patients who smoke.Pregnant and lactating mothers are excluded from the study