A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease

Inclusion criteria

All of the following conditions must be met simultaneously for enrollment:

• ① Meet the diagnostic criteria for stable angina pectoris;
• ② Classified as Grade I to III according to the Canadian Cardiovascular Society (CCS) Angina Grading Scale;
• ③ Meet the diagnostic criteria for chest discomfort syndrome due to yang qi deficiency and decline (a traditional Chinese medicine pattern differentiation);
• ④ Aged between 50 and 75 years old;
• ⑤ Received drug-eluting stent implantation due to severe vascular stenosis (single artery ≥75%， or LM ≥50%) detected by coronary angiography;
• ⑥ Able to actively comply with medical instructions and voluntarily sign the written informed consent form.

Exclusion criteria

Participants will be excluded if they meet any of the following conditions:

• ① Diagnosed with acute coronary syndrome (including acute ST-segment elevation myocardial infarction, acute non-ST-segment elevation myocardial infarction, and unstable angina pectoris) after relevant examinations;
• ② Suffer from chest pain caused by non-cardiac diseases other than stable angina pectoris; or have complicated severe hypertension (systolic blood pressure ≥ 180mmHg and/or diastolic blood pressure ≥ 110mmHg), severe cardiopulmonary insufficiency, or malignant tumor;
• ③ Have severe endocrine, hematological or rheumatic immune system diseases, severe hepatic and renal dysfunction, active gastrointestinal bleeding, or mental illness;
• ④ Have an allergic constitution or a history of allergic reactions to traditional Chinese medicine;
• ⑤ Have incomplete major baseline data that may affect the trial results, or have participated in other clinical trials recently.