A Study on the Effects of Exercise on Side Effects From Treatment for Gastrointestinal Cancers

Study staff will also confirm remote training feasibility including items such as access to Wi-Fi and a treadmill for the study duration. If patients do not have access to a treadmill, ExOnc staff may coordinate access to a fitness facility local to the participant, to facilitate treadmill access for the study duration. Fitness facility access will be provided through Wellhub, a service that allows use of nearby gyms and studios through a single app-based solution.

Inclusion criteria

• Aged ≥18 years
• Diagnosed with colorectal or esophago/gastric solid tumors as defined by one of the following:

• Histological confirmation
• As per standard of care imaging
• Scheduled to receive neoadjuvant chemotherapy or chemotherapy for newly diagnosed metastatic disease
• Performing ≤90 minutes of structured moderate-intensity or strenuous-intensity exercise per week, as evaluated by self-report
• Willingness to comply with all study-related procedures
• Cleared for exercise participation as per screening clearance via the Physical Activity Readiness Questionnaire

Exclusion criteria

• Enrollment onto any other lifestyle interventional investigational study, except interventions determined by the PI not to confound study outcomes
• Receiving treatment for any other diagnosis of invasive cancer
• Mental impairment leading to inability to cooperate
• Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for study participation