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Completed

NCT Number: NCT05832853

A Study of the Intervention Effect of a Hybrid Exercise Program on Frail Elderly

The declining physical condition of frail elderly is becoming an ugent problem. Although the exercise intensity of Wu Qin Xi appears to be low, it is highly effective in the older individuals. Inspired by the characteristics and functions of Wu Qin Xi, we designed a brand new exercise intervention training program among frail older people, which incorporates Wu Qin Xi, strength exercises and endurance exercises to improve physical fitness, and even reverse the condition of frailty. Furthermore, to improve utility in clinical practice, we innovatively employed machine learning simulations to infer the condition of older adults and predict their level of frailty after the intervention.

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Key information

Conditions

Frail Elderly Syndrome Frailty Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

60 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chinese Center of Exercise Epidemiology

Changchun, Jilin, 130024, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • a Fried frailty phenotype score of 3-5 points;
  • could walk for at least 6 min without support;
  • had not been able to walk in the past year other training.

Exclusion criteria

  • people who have a past mental illness or serious psychological issues which make it difficult to obey orders;
  • people who have had neurological disorders within the last six months;
  • people who must regularly participate in other training programs during the study period;
  • people who struggle to walk normally due to significant muscle and skeletal injuries and continuous joint discomfort.

Treatment and study plan

Wu Qin Xi exercise

Behavioral

The training schedule for Wu Qin Xi consisted of two phases: the first phase lasted for eight weeks, while the second phase lasted for 16 weeks. In the first phase, Wu Qin Xi group was given twice repetitions of the intervention. The second phase consisted of three repetitions of the Wu Qin Xi group. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

Wu Qin Xi, resistance training and endurance training

Behavioral

During the first 8 weeks, the training consists of learning and consolidating the movements of the Wu Qin Xi. In the second 16 weeks, participants perform a full set of movement exercises. Each resistance training session contained two lower-body exercises (seated calf raises and hip abduction) and three upper-body exercises (lateral pull downs, biceps curls, and triceps push downs) and two sets for each exercise. Endurance training is performed by continuous walking on an undisturbed indoor track for 15 min. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

Resistance training and endurance training

Behavioral

Each resistance training session contained two lower-body exercises (seated calf raises and hip abduction) and three upper-body exercises (lateral pull downs, biceps curls, and triceps push downs) and three sets for each exercise. Endurance training is performed by continuous walking on an undisturbed indoor track for 30 min. Participants warmed up for 20 min prior to the intervention and cooled down for 10 min at the end.

Primary outcomes

  1. Assessing the endurance of frail older adults using the six-minute walk test

    Time frame: Month 6

    Assessment of endurance in frail older adults before and after intervention using the six-minute walk test

  2. Assessing the speed of frail older adults using the ten-meter maximum walk speed

    Time frame: Month 6

    Assessment of speed in frail older adults before and after intervention using ten-meter maximum walk speed.

  3. Using handgrip strength tests to assess strength in frail older adults.

    Time frame: Month 6

    Using handgrip strength tests to assess strength in frail older adults before and after intervention

  4. Assessment of balance in frail older adults using Time Up and Go Test.

    Time frame: Month 6

    Assessment of balance in frail older adults before and after intervention using Time Up and Go Test.

Sponsors and collaborators

Lead sponsor

Guang Yang, Prof. Dr.

Other

Registry information

Official study title

Hybrid Exercise Program is Frail Elderly Need: Effectiveness on the Physical Abilities and Clinical Assistance From White Box Modeling

Important dates

Study start
2018
Primary completion
2018
Study completion
2019
First posted
Apr 27, 2023
Registry last updated
Apr 27, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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