Tianjin Medical University Cancer Institute and Hospital
Tianjin, Tianjin Municipality, 300060, China
Location status: Recruiting
NCT Number: NCT07229586
This study aims to evaluate the safety and preliminary efficacy of SHR-7367 in combination with antineoplastic agents in subjects with advanced solid tumors, and to determine the maximum tolerated dose (MTD) and the recommended Phase II dose (RP2D).
Interested in participating?
Request Info18 year–75 year
All sexes
Interventional
Phase 1 / Phase 2
Tianjin, Tianjin Municipality, 300060, China
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
SHR-7367 injection.
SHR-1316 injection.
Paclitaxel for injection (Albumin Bound).
Gemcitabine Hydrochloride for injection.
Time frame: Up to 28 days.
Time frame: About 1 year.
Time frame: About 1 year.
Time frame: Assessed every 6 weeks, about 1 year.
Time frame: Assessed every 6 weeks, about 1 year.
Complete response + Partial response (CR+PR) based on RECIST v1.1.
Time frame: Assessed every 6 weeks, about 1 year.
Complete response + Partial response + Stable disease (CR+PR+SD) based on RECIST v1.1.
Time frame: Assessed every 6 weeks, about 1 year.
Time from documentation of tumor response to disease progression assessed among patients who had an objective response.
Time frame: Assessed every 6 weeks, about 1 year.
Time from C1D1 to the first assessment of disease progression or death, whichever is earlier.
Time frame: Assessed approximately once every 1 month, about 1 year.
Time from C1D1 to the first assessment of disease progression or death, whichever is earlier.
Contact information is provided by the study sponsor or research team.
Shanghai Hengrui Pharmaceutical Co., Ltd.
Industry
A Phase IB/II Clinical Study of the Safety, Tolerability and Efficacy of SHR-7367 in Combination With Anti-tumor Agents in Subjects With Solid Tumors
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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