Recruiting

NCT Number: NCT07000864

A Study of Live Tumor Fragments of Surgical Resections

The purpose of this study is to obtain unused resected tumor tissue sample and associated clinical data from patients enrolled in this study to research ex vivo treatment response and integrity of tumor microenvironment using omics analysis and imaging while maintaining cell stability in a live environment.

Recruiting

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Key information

Conditions

Cancer Neoplasms Tumor

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States

Location status: Recruiting

Location contact

Clinical Trials Referral Office

CONTACT

[email protected]

855-776-0015

Dev Mukhopadhyay, PhD

PRINCIPAL_INVESTIGATOR

Megan Warner

CONTACT

[email protected]

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Ability to understand and sign informed consent
Planning to undergo a surgical procedure to remove cancer

Exclusion criteria

Does not meet Inclusion criteria
No tissue for research available at time of surgery

Treatment and study plan

No intervention

Other

Lab-based correlative study; no intervention

Primary outcomes

Tissue response to treatment

Time frame: Up to 72 hours

Tumor sample fragments will be treated with various combination of chemotherapy and immunotherapy drugs that are commonly used to treat patients clinically (panel of drugs will be selected based on cancer type). response to the treatment will be assessed at multiple timepoints during a 72-hour period.

Study contacts

Contact information is provided by the study sponsor or research team.

Clinical Trials Referral Office

CONTACT

[email protected]

855-776-0015

Megan Warner

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Predicting Response to Therapy From Analysis of Live Tumor Fragments of Surgical Resections

Important dates

Study start: 2025
Primary completion: 2028
Study completion: 2028
First posted: Jun 3, 2025
Registry last updated: May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting