A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.

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Key information

Conditions

Open-angle Glaucoma Cardiovascular Diseases Eye Diseases Glaucoma Glaucoma, Open-Angle Hypertension Ocular Hypertension Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

United States Investigative Sites in Texas and Other States

Fort Worth, Texas, 76180, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed with open-angle glaucoma (with ot without pseudoexfoliation or pigment dispersion component) or ocular hypertension
Other protocol-defined inclusion criteria may apply.

Exclusion criteria

Under 18
Other protocol-defined exclusion criteria may apply.

Treatment and study plan

AL-37807 Ophthalmic Suspension, 1.0%

Drug

One drop in the study eye(s) once daily for 28 days

Latanoprost, 0.005% (Xalatan)

Drug

One drop in the study eye(s) once daily for 28 days

Other names: XALATAN

AL-37807 Vehicle

Other

One drop in the study eye(s) once daily for 28 days

Timolol Maleate Ophthalmic Gel Forming Solution, 0.5%

Drug

One drop in the study eye(s) once daily for 28 days

Primary outcomes

Mean intra-ocular pressure (IOP) change at Day 28 from baseline (Day 0)

Time frame: Day 28

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Important dates

Study start: 2005
Primary completion: 2006
Study completion: 2006
First posted: Feb 7, 2006
Registry last updated: Mar 5, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed