A Study for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditions

Inclusion criteria

• Sign the informed consent form, willing to cooperate with the study, and comply with trial requirements
• Age ≥18 years, no gender restrictions
• Known or highly suspected CNS lesions, with imaging showing at least one enhanced lesion
• Scheduled for CNS contrast-enhanced MRI for clinical needs and agree to complete two contrast-enhanced MRI scans

Exclusion criteria

• Clinically unstable condition or severe diseases that may affect trial results, such as inability to ensure imaging comparability or reliability of study parameters
• Moderate to severe renal dysfunction, defined as aGFR < 60 mL/min
• Contraindications to MRI, such as metallic implants or claustrophobia
• History of severe allergies, including drugs, contrast agents, or other allergens
• Severe liver disease or cardiovascular disease, or related abnormal test results
• Central nervous system inflammation or recent history of stroke
• Active infectious diseases, such as HIV, hepatitis B, or syphilis
• Use of other contrast agents before or after study drug administration, or recent interventional treatments that may affect imaging comparability
• Pregnancy, breastfeeding, or plans for conception, without effective contraception measures
• Recent participation in other clinical trials or previous participation in studies involving gadolinium-based contrast agents
• Other conditions deemed unsuitable by the investigator