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OpenTrials
Completed

NCT Number: NCT07209137

A Single-Group Clinical Trial to Evaluate the Effects of Health Nag's BioActive Collagen Jelly on Skin, Hair, Nail, and Joint Health

This decentralized, single-arm, open-label study evaluates the effects of Health Nag's BioActive Collagen Jelly on skin, hair, nail, and joint health in 40 female participants over 12 weeks. Participants will submit online questionnaires and standardized digital photos, which will be analyzed by dermatology experts.

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Key information

Age range

30 year–55 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Citruslabs

Las Vegas, Nevada, 89118, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be female
  • Be aged 30-55.
  • Anyone who has concerns surrounding their skin health and appearance over the last four weeks.
  • Anyone who has concerns surrounding their hair health and hair fall or thinning over the last four weeks.
  • Anyone who has been using the same hair and skincare routine and products for at least one month prior to the study, i.e., shampoo, conditioner, products, cleanser, toner, and makeup remover.
  • Anyone willing to maintain the same hair and skincare routine and products throughout the 6-month trial, i.e., shampoo, conditioner, products, cleanser, toner, and makeup remover.
  • Is willing to discontinue any other supplements or herbal remedies that target skin or hair health including but not limited to collagen.
  • Anyone willing to avoid introducing any other supplements, medications, or herbal remedies for the duration of the trial.
  • Anyone who is generally healthy - does not live with any uncontrolled chronic disease.
  • Resides in the United States.
  • Not currently partaking in another research study and will not be partaking in any other research study for the next 6 months and at any point during this study's duration.
  • Anyone who owns a smartphone or camera.

Exclusion criteria

  • Anyone unwilling to follow the study protocol
  • Anyone who is planning to undergo facial treatments during the study period, including botox, dermal filler, chemical peels, etc.
  • Anyone who has undergone chemical treatments to the hair in the last three months e.g., chemical straightening, hair extensions with chemical bonding, perms, and relaxers.
  • Anyone with planned chemical treatments to the hair during the study period, e.g., chemical straightening, hair extensions with chemical bonding, perms, and relaxers.
  • Anyone currently taking any prescription medication for hair loss.
  • Anyone who has undergone any surgeries or invasive treatments in the last six months or is planning to undergo any surgeries or invasive treatments during the study.
  • Anyone who has had any major illness in the last three months.
  • Anyone who has any conditions that could affect the hair or scalp (e.g., alopecia areata)
  • Anyone who has stopped using hormonal birth control within the past month.
  • Anyone who has any chronic skin conditions on the face (e.g., eczema or psoriasis).
  • Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders.
  • Anyone with any allergies or sensitivities to any of the study product ingredients.
  • Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
  • Anyone who is vegan and/or does not consume animal products for any reason.
  • Anyone with a history of substance abuse.

Treatment and study plan

Dietary Supplement

Dietary Supplement

The supplement is intended to support improvements in skin health, hair strength, nail strength, joint health, and overall well-being.

Primary outcomes

  1. Change in Skin and Hair Health Assessed by Dermatologist Evaluation

    Time frame: Baseline to Week 12

    Assessment of changes in skin and hair health from baseline to Week 12 based on standardized digital photographs evaluated by a dermatologist.

Secondary outcomes

  1. Change in Participant-Reported Nail Strength, Joint Mobility, and Well-Being

    Time frame: Baseline, Week 2, Week 4, Week 8, and Week 12

    Self-reported changes in nail strength, joint health, muscle recovery, and overall well-being measured via study-specific online questionnaires.

Sponsors and collaborators

Lead sponsor

Nag Food Supplement Trading LLC

Industry

Collaborators

  • Citruslabs

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Oct 6, 2025
Registry last updated
Oct 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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