A Single Centre Study to Compare the Efficacy and Safety of Femtosecond Laser-Assisted Versus Manual Cataract Surgery

Inclusion criteria

• Clear corneal media
• Patients must be at least 18 years of age.

Exclusion criteria

• On a keratometric map of the cornea, the minimal and maximal K-values of the central 3mm zone must not differ by more than 5 dioptres. (exclusion criterium for Group A only)
• The maximum K- value may not exceed 60 D, the minimal value may not be smaller than 37 D. (exclusion criterium for Group A only)
• Corneal disease or pathology that precludes transmission of laser wavelength or distortion of laser light. (exclusion criterium for Group A only)
• Subjects with a poorly dilating pupil or other defect of the pupil that prevents the iris from adequate retraction peripherally.
• Lens/zonular instability such as, but not restricted to, Marfan's Syndrome, Pseudoexfoliation Syndrome, etc.
• Previous intraocular or corneal surgery of any kind, including any type of surgery for either refractive or therapeutic purposes in either eye.
• Known sensitivity to planned concomitant medications.
• Patients with disorders of the ocular muscle, such as nystagmus or strabismus
• Keratoconus
• Patients with woundhealing disorders such as connective tissue disease, autoimmune illnesses, immunodeficiency illnesses, ocular herpes zoster or simplex, endocrine diseases, lupus, rheumatoid arthritis
• Abnormal examination results from slit lamp, Fundus, IOL Master
• Abnormal examination results from Orbscan (exclusion criterium for Group A only)
• Patients with an autoimmune disease, collagenosis or clinically significant atopy.
• Patients who are pregnant or nursing.
• Patients who do not give informed consent.
• ACD < 2.4 mm or ACD > 4.5 mm as measured by ultrasonic examination (exclusion criterium for Group A only)