A Single-Center Evaluation of the Pattern of Allergic Signs and Symptoms During 4 Weeks in Ragweed Season

Subjects who had a positive skin test to ragweed within 24 months of Visit 1 were instructed to complete a diary, which assessed their allergic signs and symptoms 3 times a day for 4 weeks. During the in-office visits, subjects were asked to completed a quality of life questionnaire, as well as a retrospective and/or prospective eye allergy questionnaire.

Inclusion criteria

• Subjects must:

• be willing and able to read, sign, and date the informed consent and HIPAA documents prior to initiation of Visit 1 procedures or exams;
• be at least 18 years of age;
• be willing to avoid disallowed medication, such as anti-allergy therapies
• have a positive history of ocular allergies and a positive skin test reaction to ragweed within the past 24 months;
• have a calculated logMAR visual acuity score using the ETDRS Chart of 0.60 or better in each eye at Visit 1;

Exclusion criteria

• Subjects may not:

• have preauricular lymphadenopathy or any ocular condition that could affect study parameters (particularly, clinically significant blepharitis, follicular conjunctivitis and iritis);
• have had any ocular infection within the last 30 days;
• have a positive diagnosis of moderate to severe dry eye syndrome (i.e., requiring daily use of artificial tears);
• wear contact lenses to each office visit; Note: Subjects will be allowed to use cold compresses.