semaglutide
DrugTablet given orally
NCT Number: NCT05429593
This study will test how the active substances semaglutide and dapagliflozin act in the body (in terms of their levels in the blood), when they are taken in the form of a combination preparation (a tablet with a fixed dose combination) compared to when oral semaglutide and dapagliflozin are given alone.The study will consist of 2 parts. Part 1 will compare semaglutide to the fixed dose combination tablet (semaglutide/dapagliflozin) and part 2 will compare dapagliflozin to the fixed dose combination tablet (semaglutide/dapagliflozin). Participants will take part in either part 1 or part 2.
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Notify Me18 year–64 year
All sexes
Interventional
Phase 1
Novo Nordisk Investigational Site, Berlin, Brandenburg, Germany
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Tablet given orally
Tablet given orally
Tablet given orally
Time frame: From 0 to 24 hours on day 49 and 84 in Part 1
measured in h*nmol/L
Time frame: From 0 to 24 hours on day 49 and 98 in Part 2
measured inh*ng/mL
Time frame: From 0 to 24 hours on day 49 and 84 in Part 1
measured in nmol/L
Time frame: From 0 to 24 hours on day 49 and 98 in Part 2
measured in ng/mL
Time frame: From 0 to 24 hours on day 49 and 84 in Part 1
measured in hours
Time frame: From 0 to 24 hours on day 49 and 98 in Part 2
measured in hours
Novo Nordisk A/S
Industry
A Study Comparing Exposure of Semaglutide and Dapagliflozin Dosed Orally as Mono-components Versus in a Fixed-dose Combination
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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