Skip to main content
OpenTrials
Completed

NCT Number: NCT05479656

A Rehabilitation Program to Increase Balance and Mobility in Ataxia of Charlevoix-Saguenay

This exploratory study used a pre-post test design. The supervised rehabilitation program was performed three times a week for 8 weeks (two sessions at a rehabilitation gym and one pool session). Outcome measures included Ottawa sitting scale, 30-Second Chair Stand test, Berg Balance Scale, 10-Meter Walk Test, 6-minute Walk Test, modified Activities-specific Balance Confidence Scale and SARA scale. 10 participants will complete the training program. They will be evaluated at baseline, at week 4 (miway) and after the program.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay Spastic ataxia Charlevoix-Saguenay type

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Groupe de recherche interdisciplinaire sur les maladies neuromusculaires

Saguenay, Quebec, G7X 7X2, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Genetically confirmed ARSACS diagnosis; walker (indoor walking abilities with or without walking aids); ability to walk 10 meters; ability to provide informed consent

Exclusion criteria

  • Having other medical diagnosis causing physical limitations

Treatment and study plan

Training program

Other

8-week rehabilitation program aimed at increasing trunk and lower limb motor control on balance and walking abilities, and accomplishment of activities of daily living.

Primary outcomes

  1. Change in the Scale for the assessement and rating of ataxia (SARA)

    Time frame: Baseline, week 4, week 8

    Measured with the Scale for the assessement and rating of ataxia (SARA), score range 0-40, higher score indicates higer ataxia severity

Secondary outcomes

  1. Change in walking speed

    Time frame: Baseline, week 4, week 8

    Change in the walking speed, measured with the time to walk 10 meters at comfortable and maximum speed

  2. Change in the number of sit-to-stand performed in 30 seconds

    Time frame: Baseline, week 4, week 8

    Number of complete sit-to-stand performed in 30 seconds without the help of arms

  3. Change in the balance confidence

    Time frame: Baseline, week 4, week 8

    Measured with the modified Activities-specific Balance Confidence (ABC) Scale, score range 0-100, 0 indicates no confidence and 100 is full confidence.

  4. Change in balance

    Time frame: Baseline, week 4, week 8

    Measured with the Berg Balance Scale, score range 0-56, a higher score indicates better balance.

  5. Change in sitting balance

    Time frame: Baseline, week 4, week 8

    Measured with the Ottawa sitting scale, score range 0-40, a higher score indicates a better outcome.

  6. Change in the level of independence to perform daily living activities

    Time frame: Baseline, week 4, week 8

    Measured with the Barthel Index, score range 0-100, a higher score indicates a higher level of independence.

Sponsors and collaborators

Lead sponsor

Élise Duchesne

Other

Collaborators

  • Muscular Dystrophy Canada

Registry information

Official study title

A Better Trunk and Lower Limb Control for a Better Mobility: Assessment of a Re-entrainment Program in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Jul 29, 2022
Registry last updated
May 24, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.