A Registered Cohort Study on Neurodegenerative Associated With Sleep Disorder.

Inclusion criteria

• clinical diagnosis of neurodegenerative disease.
• patients experience insomnia, excessive drowsiness, or confusion at night.
• Patients experience frequent awakenings, daily sleep episodes, or nocturnal confusion.
• The presence of one or more of the following characteristics: a. wandering at night with inappropriate activity; b. agitation, combativeness; c. confusion, disorientation, or marked delirium.
• Polysomnographic monitoring showed the following two conditions: a. poor sleep efficiency, increased number and duration of awakenings; b. multiple sleep latency tests showed increased daytime sleepiness.
• Presence of other medical symptoms that do not indicate the primary disease.
• Other sleep disorders (e.g., periodic limb movement disorders, obstructive sleep apnea syndrome) may be present, but do not explain the patient 's main symptoms.
• any of the above can be diagnosed

Exclusion criteria

• Patients with other neurological disorders.
• Pregnant or lactating women.