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Recruiting

NCT Number: NCT04010201

A Registered Cohort Study on Brain Calcification

Brain calcification is a common neuroimaging feature in patients with metabolic, neurological, or developmental disorders, infectious diseases, traumatic or toxic history, as well as in otherwise normal older people. To understand the clinical and genetic characteristics of brain calcification, we establish a cohort of brain calcification to follow up patients with brain calcification.

Recruiting

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Key information

Conditions

Brain Calcification

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Neurology, First Affiliated Hospital Fujian Medical University

Fuzhou, Fujian, 350005, China

Location status: Recruiting

Location contact

Ning Wang, MD, PhD

SUB_INVESTIGATOR

Wan-Jin Chen, MD,PhD

PRINCIPAL_INVESTIGATOR

Wan-Jin Chen, PhD

CONTACT

[email protected]

86-0591-87982772 ext. +13860601359

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with brain calcium deposit(s) based on examinations of CT scans
  • Patients with total calcification score(TCS) greater than the physiological threshold
  • Relatives of brain calcification patients.
  • Unrelated healthy controls
  • Participants or Parent(s)/legal guardian(s) willing and able to complete the informed consent process

Exclusion criteria

  • Brain calcification caused by specific secondary factors such as infection, poisoning, and trauma
  • Participants declining or unable to comply with trial procedures and visit schedule

Treatment and study plan

Primary outcomes

  1. The incidence of hereditary brain calcification

    Time frame: Up to 20 years

    Look for the causative gene in the patient with brian calcification

Study contacts

Contact information is provided by the study sponsor or research team.

Wan-Jin Chen, PhD

CONTACT

[email protected]

86-0591-87982772

Yi Lin, PhD

CONTACT

[email protected]

86-0591-87982772

Sponsors and collaborators

Lead sponsor

Wan-Jin Chen

Other

Collaborators

  • Chang Gung Memorial Hospital
  • Taipei Veterans General Hospital, Taiwan

Registry information

Important dates

Study start
2019
Primary completion
2029
Study completion
2079
First posted
Jul 8, 2019
Registry last updated
Sep 23, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.