A Real-world Assessment in Implementation of the MASH Patient Care Pathway in Chinese Population Using the Meinian Health Check-up Database

Inclusion criteria

For All and Study population:

• Male or female, age above or equal to 18 years on health-check-up visit day
• No missing value on sex

For EASL at risk population

• Must be part of study population.
• People with T2D or [obesity＋above or equal to 1 cardiometabolic risk factor(s)] or elevated liver enzymes

For EASL not at-risk population

• Must be part of study population.

For EASL-SAFE

• Must be part of EASL at risk population

For AGA at risk population

• Must be part of study population.
• People with 2 or more metabolic risk factors (EASL-MASLD criteria) or T2D or steatosis on any imaging modality or with elevated aminotransferases

For CSH MAFLD population

• Must be part of study population.
• Liver steatosis on abdominal ultrasound
• With at least one component of Metabolic syndrome (MetS [CSH])

Exclusion criteria

• Individuals originating from centers with fewer than 100 participants
• Missing value of liver stiffness measurement (LSM)
• Had an interquartile range/median ratio above or equal to 30% of the measurement of LSM
• Missing value on either aspartate aminotransferase (AST) or alanine aminotransferase (ALT) or platelet count (PLT)
• Missing value on FPG, TG, HDLc or BP (to define the presence of metabolic risk factors)
• Missing value on abdominal ultrasound

For EASL not at-risk population 1. People with T2D or [obesity＋above or equal to 1 cardiometabolic risk factor(s)] or elevated liver enzymes

For EASL-SAFE/NFS

• Missing value on globulin