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Completed

NCT Number: NCT01789801

A Randomized Study Evaluating the Role of Ultra-sound Guidance When Drawing Radial Arterial Blood Samples

Previous studies have demonstrated that an experienced ultrasound operator is able to efficiently perform radial arterial puncture on patients where an initial operator failed to puncture arteries via simple palpation.

The objective of this study is to compare "difficult-to-puncture" patients randomized into two groups: one group where ultrasound is used to aid artery localisation, and one group where only palpation is used.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, Gard, 30029, France

About this study

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The patient must have given his/her informed and signed consent
  • The patient must be insured or beneficiary of a health insurance plan
  • The patient's health status necessitates an arterial blood sample AND his/her radial arteries are deemed unpalpable OR two previous attempts at radial arterial puncture by a nurse resulted in failure

Exclusion criteria

  • The patient is participating in another study
  • The patient is in an exclusion period determined by a previous study
  • The patient is under judicial protection, or any kind of guardianship
  • The patient refuses to sign the consent
  • It is impossible to correctly inform the patient
  • The patient is pregnant, parturient, or breastfeeding
  • Arterial puncture is required on femoral, humeral or axillary arteries
  • The patient is in cardiac arrest
  • The patient has known circulatory problems, ischemia, local infection
  • The patient has a severe bleeding or hemostasis disorder (hemophilia, hypoprothrombinemia, platelets <50,000)
  • The patient is an upper limb amputee, or his/her arm is in a cast
  • The patient has known allergies to methyl or propylbenzoate, propylene glycol or chlorexhidine gluconate

Treatment and study plan

RAP palpation only

Procedure

Skin disinfection by local antiseptic. Identification of the radial artery by palpation. Insertion of the needle positioned at 70 ° with regard to the artery palpated. Check the rise of arterial blood in the syringe.

Other names: Radial artery puncture via palpation of arteries only

RAP with ultrasound guidance

Procedure

Skin disinfection by local antiseptic. Application of sterile gel. Identification of the artery via ultrasound vascular probe. Center the artery at the center of the screen. Introduction of the syringe at 70 ° with respect to the probe, in center of visualized zone. Check the rise of arterial blood in the syringe.

Other names: radial artery puncture with ultrasound guidance.

Primary outcomes

  1. Only one attempt at arterial puncture was necessary (yes/no)

    Time frame: Day 0 - end of procedure

Secondary outcomes

  1. Number of skin punctures

    Time frame: Day 0 - end of procedure

  2. Length of time necessary for the procedure

    Time frame: Day 0 - end of procedure

  3. Presence/absence of complications

    Time frame: Day 0 - end of procedure

    Presence/absence of complications including hematoma, nerve injury, vagal reaction, pseudo-aneurysm.

  4. Patient satisfaction

    Time frame: Day 0 - end of procedure

    Patient satisfaction is evaluated using a visual analog scale.

  5. Operator satisfaction

    Time frame: Day 0 - end of procedure

    Operator satisfaction is estimated using a visual analog scale.

  6. Patient pain evaluation

    Time frame: Day 0 - end of procedure

    Patients are asked to evaluate the experienced pain level using a visual analog scale.

  7. The number of catheters used

    Time frame: Day 0 - end of procedure

  8. Was additional assistance necessary? yes/no

    Time frame: Day 0 - end of procedure

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Acronym: ECHO-PARDIF

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Feb 12, 2013
Registry last updated
Nov 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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