Skip to main content
OpenTrials
Completed

NCT Number: NCT06972277

A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs

The study compares the effectiveness of three commercial weight management programs. The primary outcome is absolute and percentage weight change at 12-weeks.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

WW International, Inc

New York, 10010, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years or older
  • BMI ≥27 kg/m²
  • Own a bodyweight scale that they can weigh themselves with during the study
  • Willing and able to comply with study protocol
  • Capable of providing informed consent
  • Able to read and write in English
  • Willing to be randomized
  • Willing to sign a Non Disclosure Agreement

Exclusion criteria

  • Pregnant, lactating, or plans to become pregnant in the next 6 months
  • Previous bariatric surgery or planned bariatric surgery during the study period
  • Major surgery within the past 6 months or plans to have surgery during the study period
  • Participation in the previous 3 months or current participation in a structured behavioral weight loss program
  • Participation in another structured weight loss program during the study period (i.e., the next 3 months)
  • Communication needs that would render them unable to understand the study and/or intervention materials
  • Current or previous history of anorexia or bulimia nervosa
  • Engagement with vomiting or laxative use within the last 28 days with the aim of controlling their shape or weight
  • Currently taking anti-obesity medications, planning to take anti-obesity medications in the next 6 months, or previously taken anti-obesity medications in the previous 3 months
  • Weight loss of ≥ 5 kg (11 lb) in the previous 6 months
  • Self-reported diagnosis of severe depression, bipolar disorder, substance abuse, or psychosis
  • Participants who are involved in any other research studies at this time
  • Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
  • Chronic/inflammatory gastrointestinal disorders (irritable bowel syndrome is acceptable)
  • History of heart problems (e.g., angina, bypass surgery, myocardial infarction, etc.) within previous 6 months
  • Diagnosis of type 1 or type 2 diabetes
  • Presence of implanted cardiac defibrillator or pacemaker
  • History of cancer within past 5 years or current treatment for cancer
  • Hospitalization for psychiatric disorders during the last 12 months

Treatment and study plan

Commercial weight management program

Behavioral

Participants will receive evidence-based behavioral / lifestyle support from a commercial weight management program.

Primary outcomes

  1. Percent body weight lost at 12 weeks

    Time frame: Baseline, 4 weeks, 8 weeks, 12 weeks

    Measurement of weight using a body weight scale

  2. Change in body weight (in kg or pounds) at 12 weeks

    Time frame: Baseline, 4 weeks, 8 weeks, 12 weeks

    Measurement of weight using a body weight scale

Secondary outcomes

  1. Physical Activity and Sedentary Behavior

    Time frame: Baseline, 12 weeks

    Global Physical Activity Questionnaire (GPAQ)

  2. Dietary intake

    Time frame: Baseline, 12 weeks

    Diet ID, powered by Diet Quality Photo Navigation (DQPN®)

  3. Hunger

    Time frame: Baseline, 12 weeks

    Hunger VAS (Visual Analogue Scale)

  4. Impact of Weight on Quality

    Time frame: Baseline, 12 weeks

    Impact of Weight on Quality of Life-Lite (IWQOL-Lite)

  5. Wellbeing

    Time frame: Baseline, 12 weeks

    World Health Organization (WHO-5)

  6. Body appreciation

    Time frame: Baseline, 12 weeks

    Body Appreciation Scale (BAS-2)

  7. Self-Compassion

    Time frame: Baseline, 12 weeks

    Self-Compassion Scale (SCS)

  8. Weight Bias Internalization

    Time frame: Baseline, 12 weeks

    Weight Bias Internalization Scale (WBIS-2F)

  9. Food cravings

    Time frame: Baseline, 12 weeks

    Food Cravings Inventory (FCI-II)

Sponsors and collaborators

Lead sponsor

WW International Inc

Industry

Registry information

Official study title

The Comparative Effectiveness of Commercial Weight Management Programs in Adults Living With Overweight or Obesity: A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 14, 2025
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.