A Prospective, Two-center, Single Arm Phase II Clinical Study to Evaluate Safety and Effectiveness of Ablation Therapy in the Treatment of Lung Cancer Presenting as Ground-glass Nodules

Inclusion criteria

• Aged between 18 and 85 years;
• GGO is diagnosed by lung CT and failure to subside after 3 months (the patient having been re-examined by thin-section CT);
• The maximum diameter of the GGO is bigger than 8mm and smaller than 3cm;
• For single GGO: obvious progress was observed in pure GGO or the solid component of mixed ground glass nodules was more than or equal to 2 mm
• The patients were unable to tolerate the operation for various reasons or multiple grinding glass nodules, operation can not be completely removed; or patients had received surgery in ipsilateral chest
• The patient is able to understand and comply with the study and has provided written informed consent

Exclusion criteria

• Patients who participated in any drug and / or medical device clinical trials within one month before the trial
• had severe disease conditions
• allergy to narcotic drugs
• had other autoimmune disease
• dementia or cognitive impairment can't cooperate with researchers
• any local treatment other than ablation was received within 4 weeks before the study