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NCT Number: NCT02640872

A Prospective Cohort Study of Aged People for Chronic Diseases

This study is a hospital-based, prospective cohort study to elucidate the predictive factors including muscle and fat mass for chronic diseases and mortality in elderly persons aged 60 years and older.

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Key information

Conditions

Aging Atrophy Bone Diseases Bone Diseases, Metabolic Cardiovascular Diseases Fractures, Bone Metabolic Diseases Muscular Atrophy Musculoskeletal Diseases Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Nutritional and Metabolic Diseases Osteoporosis Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Sarcopenia Signs and Symptoms Wounds and Injuries

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, 463-707, South Korea

About this study

This study is a hospital-based, prospective cohort study to elucidate the predictive factors among anthropometric and biochemical parameters and body composition information for chronic diseases including diabetes mellitus, myocardial infarction, stroke, osteoporosis, fracture, and cognitive dysfunction, and mortality in elderly persons aged 60 years and older.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 60 years and older
  • Capable of communication with the research team
  • Provided written informed consent

Exclusion criteria

  • Age < 60 years
  • active malignancy
  • uncompensated liver cirrhosis
  • ESRD
  • severe cognitive impairment which cannot communicate with the research term

Treatment and study plan

Primary outcomes

  1. Alll cause mortality

    Time frame: 9 years

Secondary outcomes

  1. Cardiometabolic mortality

    Time frame: 9 years

  2. Incidence of major adverse cardiac event including nonfatal myocardial infarction, nonfatal stroke, and unstable angina

    Time frame: 9 years

  3. Incidence of frailty defined by the Korean Fraility Index

    Time frame: 9 years

  4. Incidence of osteoporotic fracture

    Time frame: 9 years

  5. Incidence of cognitive dysfunction measured by minimental status examination

    Time frame: 9 years

  6. Development of sarcopenia defined by the Foundation for the National Institutes of Health (FNIH) criteria

    Time frame: 9 years

Sponsors and collaborators

Lead sponsor

Seoul National University Bundang Hospital

Other

Registry information

Official study title

A Hospital-based Prospective Cohort Study With Aged People to Elucidate Predictive Factors Including Muscle and Fat Mass for Chronic Diseases and Mortality

Acronym: HAPPY

Important dates

Study start
2015
Primary completion
2018
Study completion
2021
First posted
Dec 29, 2015
Registry last updated
Mar 30, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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