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Completed

NCT Number: NCT01595308

A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers

How daily consumption of pomegranate juice affects the concentration, morphology or motility of sperm in healthy men.

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Key information

Conditions

Male Infertility Genital Diseases Genital Diseases, Male Infertility Infertility, Male Male Urogenital Diseases Urogenital Diseases

Age range

18 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 1

Primary location

Clinical Trials Program at University of California

Los Angeles, California, 90024, United States

About this study

To determine, in this pilot study, whether daily consumption of pomegranate juice (POM) affects the concentration, morphology or motility of sperm in healthy men. The purpose of the present pilot study is to examine the hypothesis that POM may improve semen parameters in men.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 12 healthy men aged 18-40
  • normal sperm counts

Exclusion criteria

  • History of undescended testes or surgery to the scrotal contents,
  • History of marijuana or alcohol abuse, hot tub usage at least 3 months prior to entry into the study
  • No alpha adrenergic medications within two weeks of entry into the study,
  • No anabolic steroid use,
  • No anticholinergic or antimuscarinic drugs, use of colchicine, cimetidine, sulfasalazine, antipsychotics, antidepressants, immunosuppressive drugs prior use of any chemotherapeutic drugs, or UTI on screening visit.

Treatment and study plan

Pomegranate Juice

Dietary Supplement

Pomegranate juice

Primary outcomes

  1. change in sperm counts

    Time frame: Baseline and 6 months

    The primary outcome will be change in sperm counts relative to baseline with and without POM.

Secondary outcomes

  1. Change in Sperm count

    Time frame: 6 months

    The secondary outcome will be change in sperm counts relative to baseline with and without POM.

Sponsors and collaborators

Lead sponsor

POM Wonderful LLC

Industry

Registry information

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
May 10, 2012
Registry last updated
May 14, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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