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NCT Number: NCT07543861

A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.

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Key information

Conditions

Parkinson Disease Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinsonian Disorders Synucleinopathies

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Domino's Farms

Ann Arbor, Michigan, 48105, United States

Location status: Recruiting

Location contact

Miriam Bohnen, DPT

CONTACT

[email protected]

734-936-1174

About this study

For phase 1, participants will attend up to 12 4-hour sessions using the dynamic standing desk. In addition to these sessions, there will be a clinical assessment at baseline and an outcome session (endpoint assessments). In total, there will be up to 14 sessions per participant. All sessions need to be completed within 6 weeks. At the baseline session, clinical measurements will be collected. These measures will be repeated in the outcome session.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Parkinson's Disease

Exclusion criteria

  • Inability to stand or walk without an assistive device
  • History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects
  • Any other history of medical or psychiatric comorbidity, precluding safe participation in the project.
  • History of symptomatic cardiovascular or pulmonary disease
  • History of active rheumatic arthritis
  • History of stroke or other neurologic conditions with significant residual sensorimotor deficits
  • History of disabling chronic pain syndrome requiring narcotic analgesics
  • Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) <24 and significant impairment in activities of daily living)
  • Venous ulcerative stasis or severe varicosities.
  • Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.

Treatment and study plan

Dynamic Standing Desk

Device

Participants will stand at the desk for 4 hours per session. During each session, the desk will move to prompt the participant to take small steps. Participants will take breaks as needed. Each participant will complete up to 12 sessions in the span of 6 weeks.

Primary outcomes

  1. Gait Speed

    Time frame: Baseline and post-intervention (up to 6 weeks).

    Gait speed will be measured during an 8.5-meter forward walking task measured in meters per second.

  2. Movement Disorder Society-Unified Parkinson's Disease Rating Scale Part III

    Time frame: Baseline and post-intervention (up to 6 weeks).

    Clinical assessment that measures motor symptoms in Parkinson's Disease. Higher scores indicates more severe symptoms. Scores range from 0-132.

  3. Montreal Cognitive Assessment

    Time frame: Baseline and post-intervention (up to 6 weeks).

    Clinical assessment that measures cognition. Higher scores indicate better cognition. Scores range from 0-30.

  4. Timed Up and Go

    Time frame: Baseline and post-intervention (up to 6 weeks).

    Clinical assessment that measures the time it takes for a participant to stand from a chair, walk 3 meters, turn around, walk back to the chair and sit back down. Higher time indicates increased motor impairment.

  5. 5 Times Sit to Stand

    Time frame: Baseline and post-intervention (up to 6 weeks).

    Clinical assessment that measures the time it takes for a participant to sit and stand five times. Higher time indicates increased motor impairment.

Study contacts

Contact information is provided by the study sponsor or research team.

Chatkaew Pongmala, PhD

CONTACT

[email protected]

734-936-0111

Miriam Van Emde Boas, DPT

CONTACT

[email protected]

734-936-1174

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Registry information

Acronym: FOGSTAND

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 22, 2026
Registry last updated
Apr 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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