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OpenTrials
Completed

NCT Number: NCT00821002

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

The study objective is to compare IOP and safety outcomes based on plug placement (upper or lower puncta).

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Key information

Conditions

Open-angle Glaucoma Eye Diseases Glaucoma Glaucoma, Open-Angle Ocular Hypertension

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Menlo Park, California, 94025, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Over 18 years
  • Diagnosed with bilateral Open-Angle Glaucoma or Ocular Hypertension

Exclusion criteria

  • Uncontrolled medical conditions
  • Subjects who wear contact lenses
  • Subjects requiring chronic topical artificial tears, lubricants, and /or requiring any other chronic topical medications

Treatment and study plan

latanoprost

Drug

Comparison of punctal plug placement between upper and lower puncta

Primary outcomes

  1. Intraocular pressure change from baseline (mmHg)

    Time frame: 6 weeks

Secondary outcomes

  1. Number of subjects with adverse events

    Time frame: 6 weeks

Sponsors and collaborators

Lead sponsor

Mati Therapeutics Inc.

Industry

Collaborators

  • QLT Inc.

Registry information

Official study title

An Open-Label, Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug System (L-PPDS) in Subjects With Ocular Hypertension (OH) or Open-Angle Glaucoma (OAG)

Important dates

Study start
2009
Primary completion
2009
Study completion
2009
First posted
Jan 12, 2009
Registry last updated
Sep 19, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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