A Novel Lung Function Imaging Modality As a Preoperative Evaluation Tool (LIME)

To evaluate the correlation between pre-surgical 4-Dimensional Computed Tomography-ventilation (4DCT-ventilation) imaging and post-surgical lung function. To determine whether 4DCT-ventilation is a better predictor of post-surgical lung function than nuclear medicine imaging using pulmonary function tests (PFTs). To determine whether 4DCT-ventilation is a better predictor of post-surgical lung function than nuclear medicine imaging using quality of life (QOL) questionnaires. Evaluate cost-effectiveness of using 4DCT-ventialtion and VQ scans for pre-surgical assessment. To use longitudinal (pre and post-surgical) 4DCT-ventilation imaging to derive novel post-surgical prediction formulas.

Inclusion criteria

• Provision to sign and date the consent form.
• Stated willingness to comply with all required (non-optional) study procedures and be available for the duration of the study.
• Be a male or female aged 18 to 100.
• Patient with lung cancer (presumed or biopsy proven) currently undergoing or having undergone evaluation for resection.
• Lung function assessment required for pre-surgical evaluation at the discretion of the cardiothoracic surgeon.
• Life expectancy greater than 3 months.

Exclusion criteria

• Patients getting a planned wedge resection as the only thoracic resectional procedure.