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NCT Number: NCT07465523

A Novel Approach in the Evaluation of Breast Masses With Doppler US

In cases with breast masses, Doppler resistive index values will be calculated for the mass and surrounding healthy tissue and the opposite healthy breast tissue, and their effect on distinguishing between benign and malignant masses will be evaluated.

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Key information

Conditions

Breast Neoplasm Female Benign Breast Neoplasm Doppler Ultrasound Diagnosis Malign Breast Neoplasm

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Karamanoğlu Mehmetbey University, KEAH

Karaman, Lütfen Seçiniz., 70200, Turkey (Türkiye)

Location status: Recruiting

Location contact

Ahmet Yeşildağ, Prof.Dr

CONTACT

[email protected]

+905057728297

Gökçe Merve Yeşildağ, Dr

CONTACT

[email protected]

About this study

The aim of this study is to reveal the role of differences in the resistive index of masses and surrounding tissue in distinguishing between benign and malignant masses using a new approach in the evaluation of breast masses with Doppler ultrasound. The minimum, maximum, and average RI values obtained from the mass and healthy breast tissue will be recorded. The relative RI value difference will be calculated from the RI values of the mass and healthy tissue. Based on the pathology results, the cases will be divided into two groups: benign and malignant. The threshold values of these values in malignant and benign masses will be determined and compared. Additionally, vascular index values in breast masses will be calculated and compared using the relatively new Doppler Microvascular Flow method.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Those with solid breast masses
  • Female patients
  • Those with pathology results

Exclusion criteria

  • Hypovascular masses
  • Cystic breast masses
  • Cases with mastitis

Treatment and study plan

Primary outcomes

  1. A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation

    Time frame: 3-4 months

    ROC curve analysis will be applied for the diagnostic performance of relative RI change in benign and malignant lesions.

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmet Yeşildağ, Prof.Dr

CONTACT

[email protected]

+905057728297

Gökçe Merve Arman, Dr.

CONTACT

[email protected]

+905058734762

Sponsors and collaborators

Lead sponsor

Ahmet Yesildag

Other

Registry information

Official study title

A Novel Approach to the Evaluation of Breast Masses Using Doppler Ultrasonography: Percentage Changes in Resistive Index Between the Mass and Surrounding Normal Parenchyma in Benign-Malignant Differentiation

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 12, 2026
Registry last updated
Mar 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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