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OpenTrials
Completed

NCT Number: NCT02195245

A New and Innovative Method for CO2 Removal in Anesthetic Circuits: Replacing Chemical Granulate

CO2 removal is a mandatory part of modern anesthesia systems. Current chemical absorbers pose problems as the chemical granulate reacts not only with the CO2 but also the anesthetic drugs, producing organ toxic substances. The proposed CO2 absorber provides a solution to the problem of organ-toxin production in anesthetic circuits.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Queen Elizabeth II HSC, Halifax Infirmary Site

Halifax, Nova Scotia, B3H 3A7, Canada

About this study

CO2 removal is a mandatory part of modern anesthesia systems. Current chemical absorbers pose problems as the chemical granulate reacts not only with the CO2 but also the anesthetic drugs, producing organ toxic substances. The proposed CO2 absorber provides a solution to the problem of organ-toxin production in anesthetic circuits.

This new absorber can be easily integrated into any anesthesia circuit, and can effectively remove CO2 without reacting with anesthetic drugs, thus eliminating organ-toxic by-products.

It uses advanced membrane technology to separate gas flows within the circuit, separating the expensive anesthetic vapors from the CO2 (the main by-product of metabolism). Anesthetic vapors thus remain in the closed loop circuit, while CO2 is separated and exhausted to the atmosphere, rather than being absorbed through a chemical reaction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiology Physical Status Class I, II, III (low-medium risk patient)
  • English-speaking patients
  • Scheduled for elective surgery
  • Length of anesthesia ≥ 60 minutes

Exclusion criteria

  • Pregnant
  • American Society of Anesthesiology Physical Status Class IV (high risk patient)
  • Patients schedule for emergency surgery
  • Known respiratory disease, including COPD and severe asthma
  • Have elevated pressure in your brain (intra cranial pressure, ICP)

Treatment and study plan

memsorb

Device

Primary outcomes

  1. End tidal CO2 level

    Time frame: Continuous (5min intervals) over duration of anesthesia. No data collection prior or post anesthesia.

    After completion of the surgery, the digital respiration records are exported from the hospital database.

    End tidal CO2 is assessed as either in range [4.1-5.6]% or out of range <4.1% or >5.6%.

Sponsors and collaborators

Lead sponsor

DMF Medical Incorporated

Industry

Registry information

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Jul 21, 2014
Registry last updated
Oct 13, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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