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NCT Number: NCT07546461

A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface

This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the pathways required to accelerate readiness for Martian surface habitation. The protocol examines habitat resilience, radiation exposure modeling, life-support continuity, EVA logistics, behavioral health in isolated environments, and systems-engineering workflows across lunar, transit, and Mars-analog environments. Special emphasis is placed on the identification, extraction, processing, and utilization of lunar water-ice deposits as a critical resource for life-support, radiation shielding, and in-situ propellant production. Findings will inform future mission design, habitation module development, and interplanetary operational frameworks.

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Key information

About this study

This multiphase observational and operational protocol investigates the habitation lifecycle across three mission environments: (1) lunar surface habitation systems, (2) Lunar Gateway transit architecture, and (3) Martian surface analog habitats. The study integrates engineering, environmental, behavioral, and operational assessments to characterize requirements for long-duration human habitation beyond Earth orbit, with a specific focus on the role of water-ice resources in sustaining habitation and enabling interplanetary logistics.

The lunar surface phase evaluates habitat stability, environmental control and life-support system (ECLSS) resilience, radiation shielding performance, EVA logistics, mobility constraints, and dust mitigation strategies. A central component of this phase is the assessment of lunar water-ice availability, extraction feasibility, thermal stability, and processing pathways. Water-ice is evaluated as a source for potable water, oxygen generation, hydrogen production, and in-situ propellant manufacturing. Operational workflows, redundancy models, and failure-mode responses are analyzed to determine the feasibility of sustained lunar habitation supported by local resource utilization.

The Lunar Gateway phase examines transit-architecture performance, including docking operations, crew systems behavior, resource transfer workflows, and the continuity of life-support and environmental systems during transit. The study evaluates how water-ice-derived consumables from the lunar surface could be staged, processed, or transferred through the Gateway to support outbound missions. Behavioral health observations and operational stressors are assessed to understand crew performance in confined transit environments.

The Martian surface analog phase focuses on long-duration isolation, dust intrusion mitigation, power redundancy, habitat resilience, and environmental stability under Mars-analog conditions. This phase evaluates the translational pathways required to accelerate readiness for Martian habitation, including the potential use of Martian subsurface ice deposits for life-support, radiation shielding, and fuel production. Comparisons between lunar and Martian ice-resource utilization inform cross-environment operational strategies.

Across all phases, the protocol collects operational, environmental, and systems-engineering data to inform future mission architectures, habitation module design, and interplanetary habitation strategies. The study does not involve FDA-regulated products, biomedical interventions, or human subjects research as defined by federal regulations. All activities occur within controlled operational and engineering environments.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18-65
  • Able to participate in isolated, confined, or controlled operational environments
  • Prior experience in engineering, environmental systems, analog missions, or mission operations
  • Ability to perform EVA-analog tasks and operational workflows
  • Willingness to participate in multi-phase lunar, transit, and Mars-analog simulations

Exclusion criteria

  • Medical or physical limitations that prevent participation in isolated or operational environments
  • Conditions that limit safe participation in EVA-analog tasks
  • Inability to comply with operational protocols or safety requirements
  • Participation in conflicting operational studies

Treatment and study plan

Habitat Systems Evaluation

Other

Operational assessment of habitat modules, environmental stability, ECLSS resilience, redundancy models, and failure-mode responses across lunar, transit, and Mars-analog environments.

Water-Ice Resource Utilization Assessment

Other

Evaluation of water-ice identification, extraction, thermal stability, processing, and conversion into potable water, oxygen, hydrogen, and in-situ propellant.

EVA and Mobility Operations

Other

Testing of EVA logistics, mobility constraints, dust mitigation strategies, and operational workflows in lunar and Mars-analog environments.

Primary outcomes

  1. Habitat System Resilience Index (HSRI)

    Time frame: 36 months

    HSRI is a composite scale (0-100) assessing environmental stability, ECLSS uptime (%), redundancy activation success rate (%), and mean time to recovery (hours). Higher scores indicate better habitat resilience.

  2. Water-Ice Utilization Efficiency Ratio

    Time frame: 36 months

    Efficiency ratio (%) measured using the Water-Ice Processing Performance Scale (WIPPS; 0-100%), quantifying the proportion of extracted ice converted into usable water, oxygen, hydrogen, and propellant. Higher values indicate greater efficiency.

  3. Radiation Modeling Accuracy Score

    Time frame: 36 months

    Accuracy score (%) comparing predicted radiation dose (mSv) to measured dose using the Habitat Radiation Monitoring System (HRMS). Higher scores indicate greater predictive accuracy.

Secondary outcomes

  1. EVA Task Completion Time

    Time frame: 36 months

    Measured in minutes using standardized EVA Task Battery (ETB). Lower values indicate better performance.

  2. EVA Mobility Constraint Score

    Time frame: 36 months

    Assessed using the EVA Mobility Scale (0-10). Higher scores indicate greater mobility.

  3. Dust Intrusion Index

    Time frame: 36 months

    Measured using the Dust Intrusion Quantification Protocol (DIQP; 0-100). Lower scores indicate better dust mitigation.

  4. Life-Support Continuity Score (LSCS)

    Time frame: 36 months

    LSCS (0-100%) measures uninterrupted ECLSS uptime and recovery time following system faults using the ECLSS Continuity Monitoring Tool (ECMT). Higher scores indicate better continuity.

  5. Behavioral Health Stability Index (BHSI)

    Time frame: 36 months

    BHSI (0-100) assessed using the Long-Duration Behavioral Stability Scale (LDBSS). Higher scores indicate greater psychological and operational stability.

  6. Power System Uptime Percentage

    Time frame: 36 months

    Measured using the Power System Monitoring Suite (PSMS). Higher values indicate better uptime.

  7. Redundancy Activation Success Rate

    Time frame: 36 months

    Measured as % of successful automatic or manual redundancy activations.

  8. Power Recovery Time

    Time frame: 36 months

    Measured in minutes from disruption to full restoration.

  9. Particulate Intrusion Reduction Score

    Time frame: 36 months

    Measured using the Particulate Intrusion Scale (0-100). Higher scores indicate better reduction.

  10. Abrasion Resistance Index

    Time frame: 36 months

    Measured using the Surface Abrasion Test Protocol (SATP; 0-10). Higher scores indicate better resistance.

  11. Operational Degradation Rate

    Time frame: 36 months

    Measured as % decline in system performance over time. Lower values indicate better performance.

  12. Transit-to-Surface Operational Continuity Score (TSOCS)

    Time frame: 36 months

    TSOCS (0-100) measured using the Operational Continuity Assessment Tool (OCAT), evaluating workflow stability during transitions between Gateway, lunar surface, and Mars-analog environments. Higher scores indicate better continuity.

Sponsors and collaborators

Lead sponsor

Truway Health, Inc.

Industry

Registry information

Acronym: LUMEN-HAB

Important dates

Study start
2026
Primary completion
2029
Study completion
2029
First posted
Apr 22, 2026
Registry last updated
Jun 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.