A Methodological Study to Learn More About Kidney Function in Healthy People and in People With Reduced Kidney Function

Inclusion criteria

• Participant must be 18 to 75 years of age inclusive, at the time of signing the ICF.
• Stable medical condition defined as no new drug or other treatment prescribed for a chronic condition within 60 days prior to Study Day 1.
• Body weight between 50 and 100 kg.
• Female Participants: A participant is eligible to participate if not pregnant or breastfeeding. If a urine test cannot be confirmed as negative at screening (e.g., an ambiguous result), the participant must be excluded from participation.

Exclusion criteria

• Recent surgical intervention within 60 days prior to Study Day 1.
• New clinical diagnosis established within 60 days prior to Study Day 1.
• New drug prescription within 60 days prior to Study Day 1.
• Relevant change in severity of any medical condition within 60 days prior to Study Day 1, e.g. disease flare.
• Known congenital amino acid metabolism disorders.
• Severe hypersensitivity to milk products.
• Known liver cirrhosis.
• Regular use of non-steroidal anti-inflammatory drugs (NSAIDs).
• Impaired kidney function with eGFR <30 mL/min/1.73m2