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Completed

NCT Number: NCT06356337

A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1

The purpose of this research study is to investigate the relationship between reminder messages sent via text and compliance with a daily morning light intervention designed to advance the circadian clock. Twenty healthy adults will be recruited to participate in a randomized, cross-over study where daily messages are, or are not, provided to remind participants to carry out the intervention.

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Key information

Conditions

Alzheimer's Disease Alzheimer Disease Brain Diseases Central Nervous System Diseases Cognition Disorders Cognitive Dysfunction Dementia Mental Disorders Mild Cognitive Impairment Nervous System Diseases Neurocognitive Disorders Neurodegenerative Diseases Tauopathies

Age range

55 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Light and Health Research Center

Menands, New York, 12204, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy adults over the age of 55
  • score of 25 or greater on MoCA

Exclusion criteria

  • Severe sleep apnea
  • restless leg syndrome
  • obstructing cataracts
  • macular degeneration
  • diabetic retinopathy
  • glaucoma
  • use of sleep medications
  • brain disease

Treatment and study plan

Light goggles

Device

Green light goggles worn for 1 hour each morning for two weeks

Daily reminder test message

Behavioral

Participants will receive daily text message reminding them to use light goggles each morning

Primary outcomes

  1. Saliva samples for melatonin levels

    Time frame: Baseline and 2-weeks post-intervention for each Arm

    Serial saliva samples will be collected to calculate dim light melatonin onset.

Secondary outcomes

  1. Light exposure using the Speck

    Time frame: worn all 12 study weeks

    The Speck light meter will be used to collect overall light exposure.The Speck light meter uses a photosensor to measure the amount of light study participants are exposed to each day.

  2. Sleep time using actigraphy

    Time frame: worn all 12 study weeks

    Sleep time will be calculated from the actigraph. The wrist actigraph measures activity during the day and how well you sleep at night. The actigraph software will calculate the amount of time spent in bed sleeping.

Sponsors and collaborators

Lead sponsor

Icahn School of Medicine at Mount Sinai

Other

Registry information

Official study title

Light Exposure Tracker in Alzheimer's Disease.

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Apr 10, 2024
Registry last updated
Oct 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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