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NCT Number: NCT07509944

A Functional Near- Infrared Spectroscopy Study on the Brain Activation Characteristics of Stroke Patients During Mirror Movement

After the selected patients are determined, the researchers of this study need to have full communication with the patients. The location is the rehabilitation ward of our hospital and the time is

Before joining the group. During this process, the patient should be informed of the purpose, procedures and processes of the trial. The informed consent form should be signed by the patient himself/herself. Such as the patient

Illiterate, the informed consent process was witnessed by an independent witness and signed. The subject pressed their fingerprint at the signature. In the study process fully

Listen to and respond to the questions and opinions of the subjects or their representatives.

Recruiting

Interested in participating?

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • It meets the diagnostic criteria of the "Guidelines for the Prevention and Treatment of Cerebrovascular Diseases in China", and is diagnosed as cerebral infarction or cerebral hemorrhage by CT or MRI.
  • The first stroke occurred;
  • The muscle strength of the flexor and extensor muscles of the affected finger is ≤ grade 1.
  • Right-handed player
  • Muscle tone improvement: Asworth level 2 or below;
  • The disease course is within 6 months and the condition is stable.
  • Age: 18 to 75 years old, with normal vision and hearing or corrected to normal.

Exclusion criteria

  • Those with an MMSE score less than 20, severe memory, communication and speech command comprehension disorders, and those who cannot cooperate with examinations and treatments;
  • Those with a history of epilepsy;
  • Those with a history of stroke, traumatic brain injury or brain tumor in the past;
  • Those with peripheral nervous system injuries other than stroke as diagnosed by imaging;
  • Those with visual spatial impairments such as visual field defects and unilateral neglect;
  • Skull defect or metal bone plates
  • For those who are not suitable for functional near-infrared examination;
  • Those with a history of intracranial surgery.
  • Patients with lesion areas in the cerebellum or brainstem.

Treatment and study plan

mirror image

Device

Patients will be asked to place the affected hand in the mirror box. While quickly opening and closing the healthy hand, they should observe the reflection of the healthy hand in the mirror and imagine the affected hand doing the same movements.

healthy hand movement

Behavioral

Patient will be asked to quickly open and grasp the healthy hand, and keep their eyes on the affected hand.

Primary outcomes

  1. fNIRS measured brain activation

    Time frame: The measurement of the primary outcome indicators occurred after the patients had received one week of hand function rehabilitation training.

Study contacts

Contact information is provided by the study sponsor or research team.

Jiasheng Zhu, Bachelor's

CONTACT

[email protected]

+86 15157177433

Yifei Xia, master's

CONTACT

[email protected]

+86 19816890266

Sponsors and collaborators

Lead sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Other

Registry information

Important dates

Study start
2024
Primary completion
2030
Study completion
2030
First posted
Apr 3, 2026
Registry last updated
Apr 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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